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Neuroscience and Neurobiology Commons

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Utah State University

Theses/Dissertations

Brain

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Fatty Acid Induced Insulin Resistance In The Brain, Hyoung Il Oh May 2013

Fatty Acid Induced Insulin Resistance In The Brain, Hyoung Il Oh

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The prevalence of obesity is rapidly increasing; it is now one of the most serious public health problems worldwide. Obesity is thought to reflect the interaction between genetics and modern life style. In particular, high fat diets (HFD) are considered as a major contributing factor to the development of obesity and type 2 diabetes as well as other metabolic disorders such as cardiovascular disease, Alzheimer’s disease and some types of cancer. Recently, it has been suggested that insulin actions in the brain are important in the regulation of energy homeostasis and peripheral metabolism.

With the support of USTAR (The Utah …