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Full-Text Articles in Neuroscience and Neurobiology

The Influence Of Schwartz's Values On Teachers' Internet Usage: A Quantitative Study Of Cross Cultural Differences Between European Nations, Meghana Aleti Jan 2011

The Influence Of Schwartz's Values On Teachers' Internet Usage: A Quantitative Study Of Cross Cultural Differences Between European Nations, Meghana Aleti

Open Access Theses & Dissertations

This study investigated the Impact of human values on teacher Internet usage at individual levels across various nations. Schwartz's higher order values: Openness to Change, Conservation, Self-Enhancement, and Self-Transcendence are used as value variables. Teachers' are categorized as primary education, secondary education or college level. College teachers showed heavy Internet use when compared to secondary and primary teachers. Conservation higher order value was most significant among college teachers. Openness to Change and Self-Enhancement values are positively correlated with heavy Internet use among various nations. This study should be of interest to education and policy makers interested in comparison of Internet …


Gender Differences In The Processing Of Acute And Repeated Stress, Jaidee Zavala Jan 2011

Gender Differences In The Processing Of Acute And Repeated Stress, Jaidee Zavala

Open Access Theses & Dissertations

Chronic stress is implicated in the pathogenesis of a variety of diseases, including affective, immune and cardiovascular disorders, which are differentially experienced by men and women. Corticotropin-releasing factor (CRF), arginine vasopressin (AVP), and glucocorticoid receptor (GR) are the major regulators of the stress response and are widely expressed in the paraventricular nucleus of the hypothalamus (PVH), where adaptive responses to stress are generated. Adult male and female rats were subjected to single (acute) or 14 consecutive daily (repeated) 30 min restraint sessions, or maintained as unstressed controls. Rats were perfused after their final restraint, and their brain tissues sectioned and …


The Role Of Dopamine In Operant Learning And Memory, Jennifer Leigh Johnson Jan 2011

The Role Of Dopamine In Operant Learning And Memory, Jennifer Leigh Johnson

Open Access Theses & Dissertations

Dopamine is a neurotransmitter that regulates many physiological processes including reward, motivation, movement, learning and memory, and reinforcement. The cognitive processes in which one associates a specific action or behavior with a positive or negative consequence is referred to as operant learning, and is a robust occurrence in everyday life. It is also believed to play a significant role in the development of drug addiction and has been shown that increased levels of dopamine are associated with the intake of addictive drugs such as cocaine and alcohol; however, the underlying cellular mechanisms of this learned behavior are not well understood. …


Free Radical Stress-Induced Parkinsonian Lewy-Like Aggregation Prevented Through Polyphenolic Phytochemical Analog Intervention: Implications For Subcellular Trafficking And Neurodegenerative Disorders, Rituraj Pal Jan 2011

Free Radical Stress-Induced Parkinsonian Lewy-Like Aggregation Prevented Through Polyphenolic Phytochemical Analog Intervention: Implications For Subcellular Trafficking And Neurodegenerative Disorders, Rituraj Pal

Open Access Theses & Dissertations

Protein disulfide isomerase (PDI), the chief endoplasmic reticulum (ER)-resident oxidoreductase chaperone, is known to catalyze the maturation of disulfide-bond-containing proteins primarily through oxidation-reduction and isomerization functions. The rate-determining step in the oxidative regeneration path of disulfide-bond-containing proteins generally couples chemical thiol-disulfide-exchange reactions to a physical conformational folding reaction. I have determined the impact of PDI and its subdomains on the rate-determining step in ribonuclease A folding and on the physical structure-forming step of select ER-processed proteins including RNase A. This was facilitated through application of a novel chemical tool to exclusively populate native-disulfide-containing intermediates in unstructured forms. The described biochemical …