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Neuroscience and Neurobiology Commons™
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Full-Text Articles in Neuroscience and Neurobiology
The Effect Of Diazepam On Early Neural Stem Cells Proliferative Activity And Hippocampal-Dependent Memory After Traumatic Brain Injury, Van Khanh Doan
The Effect Of Diazepam On Early Neural Stem Cells Proliferative Activity And Hippocampal-Dependent Memory After Traumatic Brain Injury, Van Khanh Doan
University Honors Theses
Traumatic brain injury (TBI) induces an upregulation of neurogenesis in the brain specifically in the hippocampus, an area pertaining to learning and memory formation. Although this upregulated response is intuitively thought to be restorative, previous studies show that the nascent neurons generated after TBI exhibit abnormalities, such as aberrant morphologies and early migrations, which could suggest to be maladaptive. The GABA-A agonist diazepam has been shown to inhibit this upregulation in neurogenesis and normalizes dendrites after TBI. To determine whether this modulation of neurogenesis is ultimately beneficial or detrimental to cognitive recovery, diazepam was administered to C57BI/6J wild-type mice following …
Evaluation Of A Short-Form Of The Berg Card Sorting Test, Christopher J. Fox, Shane T. Mueller, Hilary M. Gray, Jacob Raber, Brian J. Piper
Evaluation Of A Short-Form Of The Berg Card Sorting Test, Christopher J. Fox, Shane T. Mueller, Hilary M. Gray, Jacob Raber, Brian J. Piper
Psychology Faculty Publications and Presentations
The Psychology Experimental Building Language http://pebl.sourceforge.net/Berg Card Sorting Test is an open-source neurobehavioral test. Participants (N = 207, ages 6 to 74) completed the Berg Card Sorting Test. Performance on the first 64 trials were isolated and compared to that on the full-length (128 trials) test. Strong correlations between the short and long forms (total errors: r = .87, perseverative response: r = .83, perseverative errors r = .77, categories completed r = .86) support the Berg Card Sorting Test-64 as an abbreviated alternative for the full-length executive function test.