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Articles 1 - 4 of 4
Full-Text Articles in Neuroscience and Neurobiology
Exercise As A Natural Kappa Opioid Receptor Antagonist To Treat Binge Drinking Withdrawal, Eleanor Wind
Exercise As A Natural Kappa Opioid Receptor Antagonist To Treat Binge Drinking Withdrawal, Eleanor Wind
Honors Theses
Binge drinking is a major concern, especially among college students. Positive results have been demonstrated in clinical trials that utilized exercise to treat alcohol use disorder, but questions remain regarding the type of exercise and how it should be administered across ages and sexes. Studies using animal models have investigated the neurobiological mechanisms of this treatment to improve understanding of how to implement it. One of the mechanisms under investigation is the endogenous opioid system, specifically the kappa opioid receptor (KOR) subtype. Previous research has demonstrated that exercise treatment concurrent with ethanol exposure attenuated an ethanol-induced increase in KOR receptor …
Sex-Specific Effects Of High-Fat And Ketogenic Diet On Inflammatory Responses In The Hippocampus, Shalet James
Sex-Specific Effects Of High-Fat And Ketogenic Diet On Inflammatory Responses In The Hippocampus, Shalet James
Honors Theses
Poor diet and metabolic diseases (obesity, Type 2 diabetes) are associated with increased risk of neurodegenerative and neuropsychiatric disorders, including Alzheimer’s disease, anxiety, and depression. Studies indicate that inflammation in the hippocampus could be one mechanism linking these conditions. Previous findings on inflammation, specifically glial activity in response to a high-fat diet, indicate sex differences in microglial responses in the hippocampus. The ketogenic diet is characterized by a high-fat, low-carbohydrate, and moderate-protein diet. While the ketogenic diet is very high in fat content, it may also possess neuroprotective properties against brain aging and neurodegenerative disorders, as well as boost mood …
Impacts On Fast-Start Performance: How Do Group Size And Habitat Degradation Alter The Escape Behavior Of A Schooling Coral Reef Fish?, Monica D. Bacchus
Impacts On Fast-Start Performance: How Do Group Size And Habitat Degradation Alter The Escape Behavior Of A Schooling Coral Reef Fish?, Monica D. Bacchus
All HCAS Student Capstones, Theses, and Dissertations
Escaping predation is essential for species survival, but prey must effectively match their response to the perceived threat imposed by a predator. Fish evaluate their surroundings using several sensory stimuli, including olfactory, visual, auditory, and mechanical cues. A range of taxa use the fast-start response to evade predators, including fishes, sharks, and larval amphibians. While the fast-start response (rapid bursts of swimming) is extensively studied in solitary fishes, the factors that mediate the collective escape response in schools of fish have historically been investigated far less. To address this knowledge gap, the collective escape behavior and individual escape performance of …
Analysis Of Diagnostic, Preventive, And Disease-Modifying Therapeutic Measures Of Alzheimer’S Disease, Ghazal Habib Havoutis
Analysis Of Diagnostic, Preventive, And Disease-Modifying Therapeutic Measures Of Alzheimer’S Disease, Ghazal Habib Havoutis
HCNSO Student Capstones
Alzheimer’s disease (AD) is the most common late-onset neurodegenerative disorder and cause of dementia, characterized by the formation of neurofibrillary tangles and senile plaque deposits. The heterogeneous nature of the disease (both genetically and environmentally) makes it difficult to prevent or cure. Without prevention, the prevalence of AD is expected to triple by 2050. However, because the diagnosis of AD is usually preceded by years of cognitive impairment, early detection may aid in reducing prevalence. Thus, there is a need for validated diagnostic measures for early and improved diagnosis and prevention. In this review, current and ongoing classifiers of early …