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Full-Text Articles in Neuroscience and Neurobiology
Dissociated Functional Pathways For Appetitive And Consummatory Reproductive Behaviors In Male Syrian Hamsters (Mesocricetus Auratus), Laura E. Been
Dissociated Functional Pathways For Appetitive And Consummatory Reproductive Behaviors In Male Syrian Hamsters (Mesocricetus Auratus), Laura E. Been
Neuroscience Institute Dissertations
In many species, including Syrian hamsters, male reproductive behavior depends on the perception of odor cues from conspecifics in the environment. Volatile odor cues are processed primarily by the main olfactory system, whereas non-volatile cues are processed primarily by the accessory olfactory system. Together, these two chemosensory systems mediate appetitive reproductive behaviors, such as attraction to female odors, and consummatory reproductive behaviors, such as copulation, in male Syrian hamsters. Main and accessory olfactory information are first integrated in the medial amygdala (MA), a limbic nucleus that is critical for the expression of reproductive behaviors. MA is densely interconnected with other …
Serotonergic Lesions Of The Periaqueductal Gray, A Primary Source Of Serotonin To The Nucleus Paragigantocellularis, Facilitate Sexual Behavior In Male Rats, Joseph J. Normandin, Anne Z. Murphy Phd
Serotonergic Lesions Of The Periaqueductal Gray, A Primary Source Of Serotonin To The Nucleus Paragigantocellularis, Facilitate Sexual Behavior In Male Rats, Joseph J. Normandin, Anne Z. Murphy Phd
Neuroscience Institute Faculty Publications
While selective serotonin reuptake inhibitors (SSRIs) are widely used to treat anxiety and depression, they also produce profound disruptions of sexual function including delayed orgasm/ejaculation. The nucleus paragigantocellularis (nPGi), a primary source of inhibition of ejaculation in male rats, contains receptors for serotonin (5-HT). The ventrolateral periaqueductal gray (vlPAG) provides serotonin to this region, thus providing an anatomical and neurochemical basis for serotonergic regulation of the nPGi. We hypothesize that 5-HT acting at the nPGi could underlie the SSRI-induced inhibition of ejaculation in rodents. To this end, we produced 5-HT lesions of the source of 5-HT to the nPGi (the …
Somatic Genital Reflexes In Rats With A Nod To Humans: Anatomy, Physiology, And The Role Of The Social Neuropeptides, Joseph J. Normandin, Anne Z. Murphy Phd
Somatic Genital Reflexes In Rats With A Nod To Humans: Anatomy, Physiology, And The Role Of The Social Neuropeptides, Joseph J. Normandin, Anne Z. Murphy Phd
Neuroscience Institute Faculty Publications
Somatic genital reflexes such as ejaculation and vaginocervical contractions are produced through the striated muscles associated with the genitalia. The coordination of these reflexes is surprisingly complex and involves a number of lumbosacral spinal and supraspinal systems. The rat model has proved to be an excellent source of information regarding these mechanisms, and many parallels to research in humans can be drawn. An understanding of the spinal systems involving the lumbosacral spinal cord, both efferent and afferent, has been generated through decades of research. Spinal and supraspinal mechanisms of descending excitation, through a spinal ejaculation generator in the lumbar spinal …