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Full-Text Articles in Neuroscience and Neurobiology
Contextual Modulation Of Social And Endocrine Correlates Of Fitness: Insights From The Life History Of A Sex Changing Fish, Devaleena S. Pradhan
Contextual Modulation Of Social And Endocrine Correlates Of Fitness: Insights From The Life History Of A Sex Changing Fish, Devaleena S. Pradhan
Neuroscience Institute Faculty Publications
Steroid hormones are critical regulators of reproductive life history, and the steroid sensitive traits (morphology, behavior, physiology) associated with particular life history stages can have substantial fitness consequences for an organism. Hormones, behavior and fitness are reciprocally associated and can be used in an integrative fashion to understand how the environment impacts organismal function. To address the fitness component, we highlight the importance of using reliable proxies of reproductive success when studying proximate regulation of reproductive phenotypes. To understand the mechanisms by which the endocrine system regulates phenotype, we discuss the use of particular endocrine proxies and the need for …
Nucleus Paragigantocellularis Afferents In Male And Female Rats: Organization, Gonadal Steroid Receptor Expression, And Activation During Sexual Behavior, Joseph J. Normandin, Anne Z. Murphy Phd
Nucleus Paragigantocellularis Afferents In Male And Female Rats: Organization, Gonadal Steroid Receptor Expression, And Activation During Sexual Behavior, Joseph J. Normandin, Anne Z. Murphy Phd
Neuroscience Institute Faculty Publications
The supraspinal regulation of genital reflexes is poorly understood. The brainstem nucleus paragigantocellularis (nPGi) of rats is a well-established source of tonic inhibition of genital reflexes. However, the organization, gonadal steroid receptor expression, and activity of nPGi afferents during sex have not been fully characterized in male and female rats. To delineate the anatomical and physiological organization of nPGi afferents, the retrograde tracer Fluoro-Gold (FG) was injected into the nPGi of sexually experienced male and female rats. Animals engaged in sexual behavior 1 hour before sacrifice. Cells containing FG, estrogen receptor-α (ERα), androgen receptor (AR), and the immediate-early …