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Articles 1 - 4 of 4
Full-Text Articles in Neuroscience and Neurobiology
Social Control Of Brain Morphology In A Eusocial Mammal, Melissa M. Holmes, Greta J. Rosen, Cynthia L. Jordan, Geert De Vries, Bruce D. Goldman
Social Control Of Brain Morphology In A Eusocial Mammal, Melissa M. Holmes, Greta J. Rosen, Cynthia L. Jordan, Geert De Vries, Bruce D. Goldman
Neuroscience Institute Faculty Publications
Social status impacts reproductive behavior in diverse vertebrate species, but little is known about how it affects brain morphology. We explore this in the naked mole-rat, a species with the most rigidly organized reproductive hierarchy among mammals. Naked mole-rats live in large, subterranean colonies where breeding is restricted to a single female and small number of males. All other members of the colony, known as subordinates, are reproductively suppressed. Subordinates can become breeders if removed from the colony and placed with an opposite sex partner, but in nature most individuals never attain reproductive status. We examined the brains of breeding …
Female Rats Are More Vulnerable To The Long-Term Consequences Of Neonatal Inflammatory Injury, Jamie L. Laprairie, Anne Z. Murphy Phd
Female Rats Are More Vulnerable To The Long-Term Consequences Of Neonatal Inflammatory Injury, Jamie L. Laprairie, Anne Z. Murphy Phd
Neuroscience Institute Faculty Publications
Premature infants are routinely exposed to invasive medical procedures during neonatal intensive care treatment that are largely performed in the absence of anesthetics or analgesics. Data collected to date suggest that exposure to early insult during this time of increased plasticity alters the development of the CNS and influences future pain responses. As previous studies examining the impact of neonatal injury on nociception have been conducted primarily in males, the potential adverse effects on females are not known. Therefore, the present studies were conducted to determine whether neonatal injury differentially impacts male and female sensory thresholds in adulthood. A short …
Morphine Preferentially Activates The Periaqueductal Gray – Rostral Ventromedial Medullary Pathway In The Male Rat: A Potential Mechanism For Sex Differences In Antinociception, Dayna R. Loyd, Michael M. Morgan, Anne Z. Murphy Phd
Morphine Preferentially Activates The Periaqueductal Gray – Rostral Ventromedial Medullary Pathway In The Male Rat: A Potential Mechanism For Sex Differences In Antinociception, Dayna R. Loyd, Michael M. Morgan, Anne Z. Murphy Phd
Neuroscience Institute Faculty Publications
The midbrain periaqueductal gray (PAG), and its descending projections to the rostral ventromedial medulla (RVM), provide an essential neural circuit for opioid-produced antinociception. Recent anatomical studies have reported that the projections from the PAG to the RVM are sexually dimorphic and that systemic administration of morphine significantly suppresses pain-induced activation of the PAG in male but not female rats. Given that morphine antinociception is produced in part by disinhibition of PAG output neurons, it is hypothesized that a differential activation of PAG output neurons mediates the sexually dimorphic actions of morphine. The present study examined systemic morphine-induced activation of PAG-RVM …
Role Of The Semi-Lunar Process In Locust Jumping, David W. Cofer, James Reid, Ying Zhu, Gennady Cymbalyuk, William J. Heitler, Donald H. Edwards
Role Of The Semi-Lunar Process In Locust Jumping, David W. Cofer, James Reid, Ying Zhu, Gennady Cymbalyuk, William J. Heitler, Donald H. Edwards
Neuroscience Institute Faculty Publications
We have developed a software toolkit, AnimatLab, which allows researchers to build and test virtual organisms. We used this software to build a virtual locust, and then asked how the semi-lunar process is utilized during jumping, and how manipulation or removal of the virtual SLP influences jump dynamics.