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Full-Text Articles in Neuroscience and Neurobiology
Polymorphisms Of The 5-Httlpr Gene: Associations To Ern And Depression, Curtis Killpack, Michael J. Larson
Polymorphisms Of The 5-Httlpr Gene: Associations To Ern And Depression, Curtis Killpack, Michael J. Larson
Journal of Undergraduate Research
Our aim with this study of polymorphisms in the serotonin transporter gene (5-HTTLPR) was to investigate the association between performance monitoring capabilities (i.e., detecting errors in performance using the error-related negativity [ERN] component of the scalp recorded event-related potential [ERP]) against three variations of gene 5-HTTLPR allelic pairs: homozygous short (S/S), heterozygous short-long (S/L), and homozygous long (L/L). The serotonin transporter gene is associated with our ability to cope with stress and regulate serotonin, which affects mood, social behavior, appetite, and sleep (Adam, Doane, Zinbarg, Mineka, Craske, & Griffith, 2010). Previous studies (Barnes, Dean, Nandam, O’Connell, & Bellgrove, 2011) have …
Polymorphisms Of The Glucocorticoid Receptor Gene And The Association With Stress, Randall Beck, Michael J. Larson
Polymorphisms Of The Glucocorticoid Receptor Gene And The Association With Stress, Randall Beck, Michael J. Larson
Journal of Undergraduate Research
Polymorphisms in the GR gene are an interesting and important area of research as these polymorphisms may be associated with an attenuated ability to cope with stress. This project bridged an unexplored gap between cellular and environmental stress and the expression of the GR gene—specifically the Bcl1 polymorphism of the GR gene. Cellular stress is any damage caused to the cell that alters its ability to function properly (Milisav, 2011). The Bcl1 polymorphism has what are known as C and G alleles that are genotyped as either homozygous GG, homozygous CC, or heterozygous CG (Srivastava et al., 2011). The homozygous …
Polymorphisms Of The Glucocorticoid Receptor Gene And The Association With Stress, Randall Beck, Michael J. Larson
Polymorphisms Of The Glucocorticoid Receptor Gene And The Association With Stress, Randall Beck, Michael J. Larson
Journal of Undergraduate Research
Polymorphisms in the GR gene are an interesting and important area of research as these polymorphisms may be associated with an attenuated ability to cope with stress. This project bridged an unexplored gap between cellular and environmental stress and the expression of the GR gene—specifically the Bcl1 polymorphism of the GR gene. Cellular stress is any damage caused to the cell that alters its ability to function properly (Milisav, 2011). The Bcl1 polymorphism has what are known as C and G alleles that are genotyped as either homozygous GG, homozygous CC, or heterozygous CG (Srivastava et al., 2011). The homozygous …