Neuroscience and Neurobiology Commons^™

Effects Of Methamphetamine On Microglia Through Reactive Oxygen Species, Chase Seiter, Jordan Yorgason, Nathan Sheets, James Blood, Lydia Hawley, Erin Taylor, Eliza White, Hillary Wadsworth, Jason Hansen

Library/Life Sciences Undergraduate Poster Competition 2024

▪ Dopamine release in the Nucleus Accumbens (NAc) underlies motivational behavior for methamphetamine (METH) reward.

▪ ATP is a chemoattractant to microglia and is METH on ATP release and clearance are unknown.

▪ Furthermore, METH is known to produce reactive dopamine terminal function, microglia morphology and METH interactions are unknown.

The Involvement Of The Ip3 Receptor In The Rewarding/Addictive Properties Of Methamphetamine, Mark Woodbury, Dr. Scott Steffensen

Journal of Undergraduate Research

Methamphetamine (METH) is a very powerful psychoactive drug that is highly addictive and toxic to the brain. Its use and abuse has been rising in recent years, and certain reports indicate that amphetamine-like drugs are the second most abused drugs worldwide. The side effects of METH abuse are varied and serious in nature, including: hyperthermia, tooth decay, heart attack, seizures, stroke, skin lesions, memory loss, confusion, anxiety, depression, psychosis, Parkinson’s Disease, and increased severity of HIV/AIDS (Chang et al., 2005; Curtin et al., 2015; Thanos et al., 2017). Despite these devastating effects, many of those addicted do not or cannot …