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Bowdoin College

2020

Neuromodulation

Articles 1 - 2 of 2

Full-Text Articles in Neuroscience and Neurobiology

The Role Of Behavioral Diversity In Determining The Extent To Which The Cardiac Ganglion Is Modulated In Three Species Of Crab, Grace Bukowski-Thall Jan 2020

The Role Of Behavioral Diversity In Determining The Extent To Which The Cardiac Ganglion Is Modulated In Three Species Of Crab, Grace Bukowski-Thall

Honors Projects

Central pattern generators (CPGs) are neural networks that generate the rhythmic outputs that control behaviors such as locomotion, respiration, and chewing. The stomatogastric nervous system (STNS), which contains the CPGs that control foregut movement, and the cardiac ganglion (CG), which is a CPG that controls heartbeat, are two commonly studied systems in decapod crustaceans. Neuromodulators are locally or hormonally released neuropeptides and amines that change the output patterns of CPGs like the STNS and CG to allow behavioral flexibility. We have hypothesized that neuromodulation provides a substrate for the evolution of behavioral flexibility, and as a result, systems exhibiting more …


Responses Of Central Pattern Generators In The American Lobster Stns To Multiple Members Of A Novel Neuropeptide Family, Benjamin Harley Wong Jan 2020

Responses Of Central Pattern Generators In The American Lobster Stns To Multiple Members Of A Novel Neuropeptide Family, Benjamin Harley Wong

Honors Projects

Neuropeptides are important modulators of neural activity, allowing neural networks, such as the central pattern generators (CPGs) that control rhythmic movements, to alter their output and thus generate behavioral flexibility. Isoforms of a neuropeptide family vary in physical structure, allowing potentially distinct functional neuromodulatory effects on CPG systems. While some familial neuropeptide isoforms can differentially affect a system, others in the same family may elicit indistinguishable effects. Here, we examined the effects elicited by members of a novel family of six peptide hormone isoforms (GSEFLamides: I-, M-, AL-, AM-, AV-, and VM-GSEFLamide) on the pyloric filter and gastric mill CPGs …