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Articles 1 - 11 of 11
Full-Text Articles in Neuroscience and Neurobiology
Septotemporal Variation In Theta Rhythm Dynamics: Effects Of Speed And Habituation, James Hinman
Septotemporal Variation In Theta Rhythm Dynamics: Effects Of Speed And Habituation, James Hinman
Master's Theses
Theta (6-12 Hz) field potentials and the synchronization (coherence) of these potentials present neural network indices of hippocampal physiology. Theta signals within the hippocampal formation may reflect alterations in sensorimotor integration, the flow of sensory input and/or distinct cognitive operations. While the power and coherence of theta signals vary across lamina within the septal hippocampus, limited information is available about variation in these indices across the septotemporal (long) or areal axis. The present study examined the relationship of locomotor speed to theta indices at CA1 and DG sites across the septotemporal axis as well as in the entorhinal cortex. Our …
Septal Modulation Of The Hippocampus, Siew Kian Tai
Septal Modulation Of The Hippocampus, Siew Kian Tai
Electronic Thesis and Dissertation Repository
The medial septum (MS) is the main source of acetylcholine to the hippocampus, a structure involved in memory and Alzheimer’s disease (AD). Learning and memory involve long-term changes in synaptic strengths, and are suggested to be facilitated by a brain wave, theta rhythm in the hippocampus. Since medial septal neurons influence hippocampal neural activity, lesion of two neuronal populations in the MS, cholinergic and GABAergic, was performed by intraseptal infusion of 192 IgG-saporin and orexin-saporin, respectively. I hypothesized that 1) activation of cholinergic cells by vestibular stimulation induces an atropine-sensitive theta rhythm, modulates synaptic transmission and enhances long-term potentiation (LTP), …
Map Kinases Couple Hindbrain-Derived Catecholamine Signals To Hypothalamic Adrenocortical Control Mechanisms During Glycemia-Related Challenges, Arshad M. Khan, Kimberly L. Kaminski, Graciela Sanchez-Watts, Todd A. Ponzio, J. Brent Kuzmiski, Jaideep S. Bains, Alan G. Watts
Map Kinases Couple Hindbrain-Derived Catecholamine Signals To Hypothalamic Adrenocortical Control Mechanisms During Glycemia-Related Challenges, Arshad M. Khan, Kimberly L. Kaminski, Graciela Sanchez-Watts, Todd A. Ponzio, J. Brent Kuzmiski, Jaideep S. Bains, Alan G. Watts
Arshad M. Khan, Ph.D.
No abstract provided.
The Dissociation Of Location And Object Working Memory Using Fmri And Meg, Antony Passaro
The Dissociation Of Location And Object Working Memory Using Fmri And Meg, Antony Passaro
Dissertations & Theses (Open Access)
Visual working memory (VWM) involves maintaining and processing visual information, often for the purpose of making immediate decisions. Neuroimaging experiments of VWM provide evidence in support of a neural system mainly involving a fronto-parietal neuronal network, but the role of specific brain areas is less clear. A proposal that has recently generated considerable debate suggests that a dissociation of object and location VWM occurs within the prefrontal cortex, in dorsal and ventral regions, respectively. However, re-examination of the relevant literature presents a more robust distribution suggestive of a general caudal-rostral dissociation from occipital and parietal structures, caudally, to prefrontal regions, …
Decoding Motor Intentions From Human Brain Activity, Jason P. Gallivan
Decoding Motor Intentions From Human Brain Activity, Jason P. Gallivan
Electronic Thesis and Dissertation Repository
“You read my mind.” Although this simple everyday expression implies ‘knowledge or understanding’ of another’s thinking, true ‘mind-reading’ capabilities implicitly seem constrained to the domains of Hollywood and science-fiction. In the field of sensorimotor neuroscience, however, significant progress in this area has come from mapping characteristic changes in brain activity that occur prior to an action being initiated. For instance, invasive neural recordings in non-human primates have significantly increased our understanding of how highly cognitive and abstract processes like intentions and decisions are represented in the brain by showing that it is possible to decode or ‘predict’ upcoming sensorimotor …
The Neural Substrates Of Multisensory Speech Perception, Audrey R. Nath
The Neural Substrates Of Multisensory Speech Perception, Audrey R. Nath
Dissertations & Theses (Open Access)
Comprehending speech is one of the most important human behaviors, but we are only beginning to understand how the brain accomplishes this difficult task. One key to speech perception seems to be that the brain integrates the independent sources of information available in the auditory and visual modalities in a process known as multisensory integration. This allows speech perception to be accurate, even in environments in which one modality or the other is ambiguous in the context of noise. Previous electrophysiological and functional magnetic resonance imaging (fMRI) experiments have implicated the posterior superior temporal sulcus (STS) in auditory-visual integration of …
Neural Spike Renormalization. Part I — Universal Number 1, Bo Deng
Neural Spike Renormalization. Part I — Universal Number 1, Bo Deng
Department of Mathematics: Faculty Publications
For a class of circuit models for neurons, it has been shown that the transmembrane electrical potentials in spike bursts have an inverse correlation with the intra-cellular energy conversion: the fewer spikes per burst the more energetic each spike is. Here we demonstrate that as the per-spike energy goes down to zero, a universal constant to the bifurcation of spike-bursts emerges in a similar way as Feigenbaum’s constant does to the period-doubling bifurcation to chaos generation, and the new universal constant is the first natural number 1.
Neural Spike Renormalization. Part Ii — Multiversal Chaos, Bo Deng
Neural Spike Renormalization. Part Ii — Multiversal Chaos, Bo Deng
Department of Mathematics: Faculty Publications
Reported here for the first time is a chaotic infinite-dimensional system which contains infinitely many copies of every deterministic and stochastic dynamical system of all finite dimensions. The system is the renormalizing operator of spike maps that was used in a previous paper to show that the first natural number 1 is a universal constant in the generation of metastable and plastic spike-bursts of a class of circuit models of neurons.
Orbitofrontal Cortex Provides Cross-Modal Valuation Of Self-Generated Stimuli, William A. Cunningham, Ingrid J. Haas, Ashley S. Waggoner
Orbitofrontal Cortex Provides Cross-Modal Valuation Of Self-Generated Stimuli, William A. Cunningham, Ingrid J. Haas, Ashley S. Waggoner
Department of Political Science: Faculty Publications
Prior research has shown that the orbitofrontal cortex (OFC) plays an important role in the representation of the evaluation of stimuli, regardless of stimulus modality. Based on these findings, researchers have proposed that the OFC serves a common currency function, allowing for the direct comparison of different types of perceptual stimuli (e.g. food, drink, money). The present study was designed to extend this research and investigate whether these same regions of OFC that have been identified in previous research are involved in evaluating imagined stimuli. Specifically, we asked participants to draw on prior attitudinal knowledge to generate internal representations of …
Motor Demand-Dependent Improvement In Accuracy Following Low-Frequency Transcranial Magnetic Stimulation Of Left Motor Cortex., Cathrin Buetefisch, Benjamin Hines, Linda Shuster, Paola Pergami, Adam Mathes
Motor Demand-Dependent Improvement In Accuracy Following Low-Frequency Transcranial Magnetic Stimulation Of Left Motor Cortex., Cathrin Buetefisch, Benjamin Hines, Linda Shuster, Paola Pergami, Adam Mathes
Linda Shuster
No abstract provided.
Serotonin Transporter (5-Httlpr) Genotype And Childhood Trauma Are Associated With Individual Differences In Decision Making, Scott Stoltenberg
Serotonin Transporter (5-Httlpr) Genotype And Childhood Trauma Are Associated With Individual Differences In Decision Making, Scott Stoltenberg
Scott F. Stoltenberg
The factors that influence individual differences in decision making are not yet fully characterized, but convergent evidence is accumulating that implicates serotonin (5-HT) system function. Therefore, both genes and environments that influence serotonin function are good candidates for association with risky decision making. In the present study we examined associations between common polymorphisms in the serotonin transporter gene (SLC6A4; 5-HTTLPR and rs25531), the experience of childhood trauma and decision making on the Iowa gambling task (IGT) in 391 (64.5% female) healthy Caucasian adults. Homozygosity for the 5-HTTLPR L allele was associated with riskier decision making in the first block of …