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- Cat (2)
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- Audiovisual integration (1)
- Audiovisual perception (1)
- Auditory cortex (1)
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- Cortex (1)
- Cortical thickness (1)
- Crossmodal plasticity (1)
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- Lateral extrastriate visual cortex (1)
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Articles 1 - 4 of 4
Full-Text Articles in Neuroscience and Neurobiology
Multisensory Responses In Primary Auditory Cortex Of The Cat, Catherine Boucher
Multisensory Responses In Primary Auditory Cortex Of The Cat, Catherine Boucher
Electronic Thesis and Dissertation Repository
Core auditory cortex of the cat is comprised of primary auditory cortex (A1) and the anterior auditory field (AAF). Neurons in both fields respond strongly to acoustic stimuli and are tonotopically organized. In hearing animals, a small number of cells in AAF respond to tactile stimulation. However, it is unclear if multisensory input influences responses in A1. In this study, multisensory stimuli were developed by pairing a pure tone stimulus with a flash stimulus at various stimulus onset asynchronies. A linear multielectrode array recorded multi-unit activity in A1 across cortical layers. We identified unisensory auditory, unisensory visual, bimodal, and subthreshold …
Differential Thickening And Thinning Of Auditory Cortex In Deaf Cats Revealed With Ultra-High-Field Mri, Stephen G. Gordon
Differential Thickening And Thinning Of Auditory Cortex In Deaf Cats Revealed With Ultra-High-Field Mri, Stephen G. Gordon
Electronic Thesis and Dissertation Repository
In the absence of hearing, the brain must adapt and repurpose the former auditory cortex. In this study we scanned normal hearing (n=29) and deaf (n=26) cats to identify cortical areas of differing thickness using the auditory regions from a 3D cortical atlas. Compared to hearing controls, differential thickening and thinning was observed in specific regions of the deaf auditory cortex. More dorsal auditory regions tended to be bilaterally thicker in the deaf group, while more ventral regions in the left hemisphere were thinner. The location and nature of these changes creates a gradient along the dorsoventral axis wherein dorsal …
Ultra-High Field Magnetic Resonance Imaging For Stereotactic Neurosurgery, Jonathan Lau
Ultra-High Field Magnetic Resonance Imaging For Stereotactic Neurosurgery, Jonathan Lau
Electronic Thesis and Dissertation Repository
Stereotactic neurosurgery is a subspecialty within neurosurgery concerned with accurate targeting of brain structures. Deep brain stimulation (DBS) is a specific type of stereotaxy in which electrodes are implanted in deep brain structures. It has proven therapeutic efficacy in Parkinson’s disease and Essential Tremor, but with an expanding number of indications under evaluation including Alzheimer’s disease, depression, epilepsy, and obesity, many more Canadians with chronic health conditions may benefit. Accurate surgical targeting is crucial with millimeter deviations resulting in unwanted side effects including muscle contractions, or worse, vessel injury. Lack of adequate visualization of surgical targets with conventional lower field …
Cortical Plasticity Following Adult-Onset Hearing Loss, Ashley L. Schormans
Cortical Plasticity Following Adult-Onset Hearing Loss, Ashley L. Schormans
Electronic Thesis and Dissertation Repository
The consequences of hearing loss are not confined to how the central auditory system processes sound; crossmodal plasticity also occurs, which is characterized by an increased responsiveness of neurons in auditory areas to visual and/or tactile stimuli. In the primary auditory cortex, partial hearing loss causes a decrease in the number of auditory-responsive neurons, as well as an increase in multisensory neurons. However, it was relatively unknown how adult-onset hearing loss affected cortical areas that are already capable of integrating multisensory information, such as the lateral extrastriate visual cortex (V2L). Using a combination of in vivo electrophysiology, neuropharmacology and behavioural …