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Systems Neuroscience

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Electrophysiology

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Characterizing The Cortical Contributions To Working Memory-Guided Obstacle Locomotion, Carmen Wong Sep 2018

Characterizing The Cortical Contributions To Working Memory-Guided Obstacle Locomotion, Carmen Wong

Electronic Thesis and Dissertation Repository

While walking in complex environments, the ability to acquire information about objects in our surroundings is essential for successful obstacle negotiation. Furthermore, the ease with which most animals can traverse cluttered terrain while grazing, exploring, or hunting is facilitated by the capacity to store obstacle information in working memory (WM). However, the underlying neural substrates supporting such complex behaviours are poorly understood. Therefore, the goal of this thesis is to examine the neural underpinnings of WM-guided obstacle negotiation in the walking cat.

Obstacle locomotion was studied in two main paradigms, characterized by whether obstacle presence was detected via vision or …