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Full-Text Articles in Neuroscience and Neurobiology

Spinal Cord Control Of Ejaculatory Reflexes In Male Rats, Natalie Kozyrev Jul 2013

Spinal Cord Control Of Ejaculatory Reflexes In Male Rats, Natalie Kozyrev

Electronic Thesis and Dissertation Repository

Ejaculatory dysfunction impacts large numbers of men of all ages and around the world. In addition, a great majority of men with chronic spinal cord injury (SCI) experience ejaculatory dysfunction, which negatively impacts the quality of life of these individuals and their partners. SCI men emphasize the significance of regaining sexual function as their main goal. Currently, there is a marked absence of literature reporting the alterations to sexual function and ejaculation in particular in animal models of chronic SCI. In addition, there are many unanswered questions pertaining to the spinal cord control of ejaculation in healthy, intact men. It …


Loss Of Dendritic Inhibition In The Hippocampus After Repeated Early-Life Hyperthermic Seizures In Rats., Richard Boyce, L Stan Leung Jan 2013

Loss Of Dendritic Inhibition In The Hippocampus After Repeated Early-Life Hyperthermic Seizures In Rats., Richard Boyce, L Stan Leung

Physiology and Pharmacology Publications

Seizures are relatively common in children and are a risk factor for subsequent temporal lobe epilepsy. To investigate whether early-life seizures themselves are detrimental to the proper function of the adult brain, we studied whether dendritic excitation and inhibition in the hippocampus of adult rats were altered after hyperthermia-induced seizures in immature rats. In particular, we hypothesized that apical dendritic inhibition in hippocampal CA1 pyramidal cells would be disrupted following hyperthermia-induced seizures in early life. Seizure rats were given three hyperthermia-induced seizures per day for three days from postnatal day (PND) 13 to 15; control rats were handled similarly but …