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Full-Text Articles in Neuroscience and Neurobiology

Computational Modeling Of Biological Neural Networks On Gpus: Strategies And Performance, Byron Galbraith Jul 2010

Computational Modeling Of Biological Neural Networks On Gpus: Strategies And Performance, Byron Galbraith

Master's Theses (2009 -)

Simulating biological neural networks is an important task for computational neuroscientists attempting to model and analyze brain activity and function. As these networks become larger and more complex, the computational power required grows significantly, often requiring the use of supercomputers or compute clusters. An emerging low-cost, highly accessible alternative to many of these resources is the Graphics Processing Unit (GPU) - specialized massively-parallel graphics hardware that has seen increasing use as a general purpose computational accelerator thanks largely due to NVIDIA's CUDA programming interface. We evaluated the relative benefits and limitations of GPU-based tools for large-scale neural network simulation and …


Robust Dynamic Balance Of Ap-1 Transcription Factors In A Neuronal Gene Regulatory Network., Gregory M Miller, Babatunde A Ogunnaike, James S Schwaber, Rajanikanth Vadigepalli Jan 2010

Robust Dynamic Balance Of Ap-1 Transcription Factors In A Neuronal Gene Regulatory Network., Gregory M Miller, Babatunde A Ogunnaike, James S Schwaber, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: The octapeptide Angiotensin II is a key hormone that acts via its receptor AT1R in the brainstem to modulate the blood pressure control circuits and thus plays a central role in the cardiac and respiratory homeostasis. This modulation occurs via activation of a complex network of signaling proteins and transcription factors, leading to changes in levels of key genes and proteins. AT1R initiated activity in the nucleus tractus solitarius (NTS), which regulates blood pressure, has been the subject of extensive molecular analysis. But the adaptive network interactions in the NTS response to AT1R, plausibly related to the development of …


Metastability And Plasticity In A Conceptual Model Of Neurons, Bo Deng Jan 2010

Metastability And Plasticity In A Conceptual Model Of Neurons, Bo Deng

Department of Mathematics: Faculty Publications

For a new class of neuron models we demonstrate here that typical membrane action potentials and spike-bursts are only transient states but appear to be asymptotically stable; and yet such metastable states are plastic — being able to dynamically change from one action potential to another with different pulse frequencies and from one spike-burst to another with different spike-per-burst numbers. The pulse and spike-burst frequencies change with individual ions’ pump currents while their corresponding metastable-plastic states maintain the same transmembrane voltage and current profiles in range. It is also demonstrated that the plasticity requires two one-way ion pumps operating in …


Cortical Underconnectivity Coupled With Preserved Visuospatial Cognition In Autism: Evidence From An Fmri Study Of An Embedded Figures Task, Saudamini Damarla, Timothy A. Keller, Rajesh K. Kana, Vladimir L. Cherkassky, Diane L. Williams, Nancy J. Minshew, Marcel Adam Just Dec 2009

Cortical Underconnectivity Coupled With Preserved Visuospatial Cognition In Autism: Evidence From An Fmri Study Of An Embedded Figures Task, Saudamini Damarla, Timothy A. Keller, Rajesh K. Kana, Vladimir L. Cherkassky, Diane L. Williams, Nancy J. Minshew, Marcel Adam Just

Marcel Adam Just

No abstract provided.


A Neurosemantic Theory Of Concrete Noun Representation Based On The Underlying Brain Codes, Marcel Adam Just, Vladimir L. Cherkassky, Sandesh Aryal, Tom M. Mitchell Dec 2009

A Neurosemantic Theory Of Concrete Noun Representation Based On The Underlying Brain Codes, Marcel Adam Just, Vladimir L. Cherkassky, Sandesh Aryal, Tom M. Mitchell

Marcel Adam Just

No abstract provided.