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Full-Text Articles in Neuroscience and Neurobiology
Navigating The "Little Brain": Comprehensive Mapping Of Functional Organisation, Maedbh King
Navigating The "Little Brain": Comprehensive Mapping Of Functional Organisation, Maedbh King
Electronic Thesis and Dissertation Repository
Two decades of neuroimaging research suggests that the cerebellum is functionally involved in a range of cognitive and motor processes. However, missing from the literature is a comprehensive map detailing a clear functional organisation of the cerebellum. Previous studies have used a restricted task-mapping approach to localise task-specific functional activation to cerebellar lobules. However, this approach, which is often limited to one or two functional domains within individual subjects, fails to characterise the full breadth of functional specialisation within the cerebellum. To overcome this restricted task-mapping problem, we tested 17 subjects on a condition-rich task battery (61 task conditions) across …
Functional Connectivity In The Motor Network Largely Matures Before Motor Function, Jordynne L V Ropat
Functional Connectivity In The Motor Network Largely Matures Before Motor Function, Jordynne L V Ropat
Electronic Thesis and Dissertation Repository
The brain changes in many ways in the first year. It is not known which of these changes are most critical for the development of cognitive functions. According to the Interactive Specialization Theory, developments in behaviour result from changes in brain connectivity. We tested this using functional connectivity magnetic resonance imaging (fcMRI) of the motor system. fcMRI was acquired at three and nine months – two time-points between which motor behaviour develops enormously. Infants were additionally compared with adults. Subjects were scanned with a 3T MRI scanner, yielding BOLD signal time-courses that were correlated with one another. Our results do …