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Full-Text Articles in Neuroscience and Neurobiology

Phenotyping Regression In A Female Mouse Model For Rett Syndrome Using Computational Neuroethology Tools, Michael J. Mykins Aug 2023

Phenotyping Regression In A Female Mouse Model For Rett Syndrome Using Computational Neuroethology Tools, Michael J. Mykins

Doctoral Dissertations

Regression is defined as loss of acquired skills over time and is a key feature of many neurodevelopmental disorders such as Rett syndrome (RTT). RTT is caused by mutations in the X-linked gene Methyl CpG-Binding Protein 2 (MECP2) and is characterized by a period of typical development with subsequent regression of previously acquired motor and speech skills in girls. In human and animal models, it is clear syndromic phenotypes are dynamic over time but phenotyping regression over time in animal models has remained elusive. Lack of established timelines to study the molecular, cellular, and behavioral features of regression in female …


Differentiation Of Neurons And Glia For Use In Cellular Connectomics, Jacob T. Brettin Dec 2018

Differentiation Of Neurons And Glia For Use In Cellular Connectomics, Jacob T. Brettin

Chancellor’s Honors Program Projects

No abstract provided.