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Full-Text Articles in Neuroscience and Neurobiology
Characterization Of A Putative Glycinergic Nigropallidal Pathway In The Rodent Brain, Rosalia Ortega
Characterization Of A Putative Glycinergic Nigropallidal Pathway In The Rodent Brain, Rosalia Ortega
Open Access Theses & Dissertations
Glycinergic neurotransmission is essential for the function of sensory and motor systems associated with pain transmission and rhythmic motor patterns. Yet, the way glycinergic circuits modulates motor systems via the globus pallidus external (GPe) is not clear. The cyto-architecture of glycinergic circuitry is poorly understood and most work has focused in brainstem areas. It is believed that glycinergic neurons are mainly interneurons regulating local circuits. However, it is now becoming clear that they are also projection neurons, constituting true neuronal circuits. At the glycinergic synapse, termination of neurotransmission and recycling of glycine is regulated by two transporters, glycine transporter 1 …
The Role Of The Dopamine/Ecdysteroid Receptor Dopecr In Ethanol Induced Behavioral Disinhibition, Gissel Pryscilla Aranda
The Role Of The Dopamine/Ecdysteroid Receptor Dopecr In Ethanol Induced Behavioral Disinhibition, Gissel Pryscilla Aranda
Open Access Theses & Dissertations
Ethanol, a main active ingredient of alcoholic beverages, exerts numerous effects on behavior through its interaction with diverse membrane and signaling molecules and effector cells. The effects include lack of motor control, behavioral disinhibition, tolerance, sensitization and addiction. In particular, behavioral disinhibition is typically associated with heavy drinking and can lead to detrimental consequences such as car accidents, violent rages, risky sexual behavior and illegal substance abuse. This research aimed to clarify the neural elements and cellular mechanisms underlying behavioral disinhibition induced by ethanol. The neurotransmitter dopamine (DA) is implicated in ethanol-induced behavioral disinhibition (Van Gaalen et al., 2006). To …