Open Access. Powered by Scholars. Published by Universities.®
Neuroscience and Neurobiology Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Neuroscience and Neurobiology
Limitations On Spatial Memory In Mice, Robert H.I. Dale, Martin Bedard
Limitations On Spatial Memory In Mice, Robert H.I. Dale, Martin Bedard
Robert H. I. Dale
Rats have an impressive ability to remember locations they have visited. Two experiments used an eight-arm radial maze to determine whether mice showed two important characteristics of this spatial memory: its durability, and its dependence on stimuli outside the maze (extreme stimuli). In Experiment 1, food-deprived mice were allowed to eat from four of the eight arms of the maze then, after delays of 5 sec, 1 min, or 5 min, they were permitted to choose the remaining arms. Choice accuracy declined significantly with the longer delays, but always remained above chance. In Experiment 2, the maze was rotated 180° …
Radial-Maze Performance In The Rat Following Lesions Of Posterior Neocortex, Melvyn A. Goodale, Robert H.I. Dale
Radial-Maze Performance In The Rat Following Lesions Of Posterior Neocortex, Melvyn A. Goodale, Robert H.I. Dale
Robert H. I. Dale
The present experiment was designed to investigate the role of posterior neocortex (areas 17, 18 and 18a) in the maintenance of performance on the radial maze. Following training to criterion on the 8-arm radial maze, rats received either sham operations, bilateral eye enucleations, lesions of posterior neocortex, or combined enucleations and lesions of posterior neocortex. While the enucleated animals with intact brains showed a slight, but significant performance decrement relative to the sham-operated group, the other two groups, with lesions of areas 17, 18 and 18a, each showed a massive deficit. This large deficit was observed even in the group …
Parallel-Arm Maze Performance Of Sighted And Blind Rats: Spatial Memory And Maze Structure, Robert H.I. Dale
Parallel-Arm Maze Performance Of Sighted And Blind Rats: Spatial Memory And Maze Structure, Robert H.I. Dale
Robert H. I. Dale
Sighted and peripherally blinded groups of rats learned to obtain a small reward from each arm of an eight-arm parallel maze, and a sighted group was similarly trained on a radial maze. The parallel-sighted and parallel-blind groups were equally slow, and much slower than the radial-sighted group, to attain criterion performance. The three groups shared several response characteristics: selectively avoiding the most recently entered arms, frequently choosing adjacent arms, and an absence of 'spatial generalization' among the arms. The findings support a simple model proposing how subjects identify and choose among the maze-arms.