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Full-Text Articles in Microbiology

Improving The Analysis Of T Cell Movement, Viktor Zenkov May 2018

Improving The Analysis Of T Cell Movement, Viktor Zenkov

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Vaccine-induced T cells play an important role in combating malaria by eliminating infection in the liver stage. However, as millions of hepatocytes inhabit a mouse liver and only some are infected, how T cells locate the infection site and eliminate infection remains poorly understood. Are T cells moving intentionally toward parasites, or randomly successful? To answer this, I used timed position data of malaria-specific T cells, non-specific control T cells, and a parasite, obtained from experiments in a mouse liver; I performed analyses with the null hypothesis that T cells move randomly. I used two metrics, based on distances from …


Synechococcus As An Hooh-Consuming Helper For Prochlorococcus, Abigail Mcgettigan Jarratt May 2018

Synechococcus As An Hooh-Consuming Helper For Prochlorococcus, Abigail Mcgettigan Jarratt

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

The marine cyanobacterium Prochlorococcus is an abundant and globally important microbe that contributes an estimated 40% of bacterial production in the oligotrophic ocean. The success of this photosynthetic bacterium is largely a consequence of its small cell size and streamlined genome, which are advantageous in nutrient-limited environments. However, this genomic streamlining has also led to the loss of the gene (katG) encoding catalase, an enzyme that is essential for the degradation and detoxification of the reactive oxygen species hydrogen peroxide (HOOH). HOOH is naturally present in the illuminated waters of the ocean, and in the absence of catalase, Prochlorococcus is …


Determining If Host Serum Igg Titer Is Associated With Toxoplasma Gondii Virulence, Riley E Byrd May 2018

Determining If Host Serum Igg Titer Is Associated With Toxoplasma Gondii Virulence, Riley E Byrd

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Toxoplasma gondii is a protozoan parasite that causes the disease toxoplasmosis in animals and humans. One third of the world’s human population is chronically infected with this parasite (1). Toxoplasma gondii has two infectious forms: oocysts shed in the feces of felids (domestic and wild cats) and tissue cysts in chronically infected animals (Figure 1). Humans may become infected via ingestion of food or water contaminated with oocysts, the consumption of tissue cysts in undercooked meats, or vertical transmission from the mother to the fetus. Previous studies have found that T. gondii strains from South America are genetically diverse from …


Isolation And Identification Of A Chloromethane-Degrading Bacterium From A Strictly Anaerobic Mixed Culture, Samiha Sadruddin May 2018

Isolation And Identification Of A Chloromethane-Degrading Bacterium From A Strictly Anaerobic Mixed Culture, Samiha Sadruddin

Chancellor’s Honors Program Projects

No abstract provided.


Determining If Host Serum Igg Titer Is Associated With Toxoplasma Gondii Virulence, Riley E Byrd May 2018

Determining If Host Serum Igg Titer Is Associated With Toxoplasma Gondii Virulence, Riley E Byrd

Chancellor’s Honors Program Projects

No abstract provided.


Interactions And Growth Dynamics Of Prochlorococcus, Rhodospirilaceae, And Alteromonas In A Coculture Environment, Vasily Giovanni Carniello Apr 2018

Interactions And Growth Dynamics Of Prochlorococcus, Rhodospirilaceae, And Alteromonas In A Coculture Environment, Vasily Giovanni Carniello

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Interactions between different species of microorganisms have a significant role in the growth dynamics within the environment. (Morris 08) The specifics mechanisms of these interactions, however, are overall poorly understood. The purpose of this study is to study the interactions between the heterotrophs Rhodospirilaceae (EZ54), and Alteromonas (EZ55) and the cyanobacterium Prochlorococcus (Vol 1). Here we establish the effects the cyanobacterium has on the growth dynamics of each of the heterotrophs as well as the effect the two heterotrophs have on one another.