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Microbiology Commons™

Open Access. Powered by Scholars. Published by Universities.®

2012

University of Nevada, Las Vegas

Articles 1 - 7 of 7

Full-Text Articles in Microbiology

Measuring Population Transmission Potential For Hiv: An Alternative Metric Of Transmission Risk In Men Who Have Sex With Men (Msm) In The Us, Colleen F. Kelley, Eli S. Rosenberg, Brandon M. O'Hara, Paula M. Frew, Travis Sanchez, John L. Peterson, Carlos Del Rio, Patrick S. Sullivan Dec 2012

Measuring Population Transmission Potential For Hiv: An Alternative Metric Of Transmission Risk In Men Who Have Sex With Men (Msm) In The Us, Colleen F. Kelley, Eli S. Rosenberg, Brandon M. O'Hara, Paula M. Frew, Travis Sanchez, John L. Peterson, Carlos Del Rio, Patrick S. Sullivan

Environmental & Occupational Health Faculty Publications

Background Various metrics for HIV burden and treatment success [e.g. HIV prevalence, community viral load (CVL), population viral load (PVL), percent of HIV-positive persons with undetectable viral load] have important public health limitations for understanding disparities. Methods and Findings Using data from an ongoing HIV incidence cohort of black and white men who have sex with men (MSM), we propose a new metric to measure the prevalence of those at risk of transmitting HIV and illustrate its value. …See full text for complete abstract.

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Anti-Germinants As A New Strategy To Prevent Clostridium Difficile Infections, Amber Janece Howerton Dec 2012

Anti-Germinants As A New Strategy To Prevent Clostridium Difficile Infections, Amber Janece Howerton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Clostridium difficileinfections (CDI) have emerged as a leading cause of hospital-associated complications. CDI is the major cause of antibiotic-related cases of diarrhea and nearly all cases of pseudomembranous colitis. The infective form of C. difficileis the spore, a dormant and hardy structure that forms under stress. Germination of C. difficile spores into toxin producing bacteria in the GI tract of susceptible patients is the first step in CDI establishment. Patient susceptibility occurs with a disruption of the natural gut microbiota by broad-spectrum antibiotics. Antibiotic treatments usually resolve CDI but refractory cases are on the rise. Of great concern is the …

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Nitrite Oxidation In Geothermal Springs: Evidence Of An Upper Temperature Limit For Thermophilic Nitrite-Oxidizing Bacteria Of 60 - 65 °C, Tara Edwards Dec 2012

Nitrite Oxidation In Geothermal Springs: Evidence Of An Upper Temperature Limit For Thermophilic Nitrite-Oxidizing Bacteria Of 60 - 65 °C, Tara Edwards

UNLV Theses, Dissertations, Professional Papers, and Capstones

Despite growing evidence of the importance of nitrification in terrestrial geothermal environments, little is known about nitrite oxidation in these environments. In order to further our knowledge, this study combined cultivation-dependent and -independent approaches with measurements of nitrogen speciation along the outflow channels of two Great Basin geothermal springs. Enrichment cultures were inoculated with sediment slurries from sites ranging in temperature from 42 - 87 °C at the sources and along the outflows of >15 hot springs. While attempts to enrich nitrite-oxidizing bacteria (NOB) from sites greater than or equal to 61 °C were unsuccessful, NOB were enriched from five …

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Natural And Lignocellulose-Enriched Microbial Communities In Great Boiling Spring, Nv, Jessica Cole Dec 2012

Natural And Lignocellulose-Enriched Microbial Communities In Great Boiling Spring, Nv, Jessica Cole

UNLV Theses, Dissertations, Professional Papers, and Capstones

The natural microbial communities present in Great Boiling Spring were investigated and contrasted against those present after in situ enrichment with lignocellulose. High-throughput cultivation-independent DNA sequencing of the V8 region of the small subunit (SSU) rRNA gene generated a total of 274,119 quality-filtered pyrosequencing fragments. Twelve natural spring samples were analyzed, including four high-temperature water samples and eight sediment samples ranging from 87 - 62 °C. Eight lignocellulosic enrichments incubated in the spring sediment and water at two high-temperature sites were analyzed. The natural water communities were found to be extremely uneven but relatively constant throughout time. The natural sediment …

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Effects Of Moisture Augmentation Of Municipal Solid Waste Through Addition Of Food Waste Or Wastewater Treatment Biosolids On Bio-Gas Formation For Power Generation, Jared Michael Gore Aug 2012

Effects Of Moisture Augmentation Of Municipal Solid Waste Through Addition Of Food Waste Or Wastewater Treatment Biosolids On Bio-Gas Formation For Power Generation, Jared Michael Gore

UNLV Theses, Dissertations, Professional Papers, and Capstones

An investigation into the effect of moisture augmentation by manipulation of food waste proportion or wastewater treatment plant biosolids proportion was undertaken to determine the effects on production of methane and other biogases from municipal solid waste (MSW). Laboratory microcosm experiments were performed to determine the effect of various proportions of influent waste streams on the production of biogas. Results indicated that moisture augmentation through the addition of food waste to MSW increases the overall bio-gas and hydrogen gas formed during fermentation. Moisture augmentation through addition of wastewater treatment bio-solids lead to inconclusive results. Addition of food waste to MSW …

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Assessment Of A Microbicide Candidate Among A Diverse Cohort Of Urban Southern Us Women And Their Male Sexual Partners, Paula M. Frew, Kimberly Parker, Takeia Horton, Brooke Hixson, Lisa Flowers, Frances Priddy, Lisa Grohskopf, Christine Mauck, Kimberly Workowski Jul 2012

Assessment Of A Microbicide Candidate Among A Diverse Cohort Of Urban Southern Us Women And Their Male Sexual Partners, Paula M. Frew, Kimberly Parker, Takeia Horton, Brooke Hixson, Lisa Flowers, Frances Priddy, Lisa Grohskopf, Christine Mauck, Kimberly Workowski

Environmental & Occupational Health Faculty Publications

Background: This mixed methods study reports on product acceptance from a Phase I clinical trial of a candidate non-nucleoside reverse transcriptase inhibitor (NNRTI) vaginal microbicide product (UC781). The product was evaluated in the context of a Phase I clinical trial in an area characterized by high HIV prevalence among minority women. The findings will inform the development of an acceptable microbicide that will address the needs of diverse women and their partners. Methods: This is a mixed methods study of 34 racially and ethnically diverse female participants and 10 male partners in Atlanta, Georgia. Chi-square tests for marginal homogeneity and …

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Survey Of Glycerol Dialkyl Glycerol Tetraethers (Gdgts) In Nevada And California Hot Springs And Selected T Thermophiles, Julienne J. Paraiso, Amanda Jean Williams, Brian P. Hedlund, Chuanlun L. Zhang Jan 2012

Survey Of Glycerol Dialkyl Glycerol Tetraethers (Gdgts) In Nevada And California Hot Springs And Selected T Thermophiles, Julienne J. Paraiso, Amanda Jean Williams, Brian P. Hedlund, Chuanlun L. Zhang

McNair Poster Presentations

Glycerol dialkyl glycerol tetraethers (GDGTs) are core membrane lipids of many Archaea and some Bacteria found ubiquitously in soils and in many aqueous environments. Here, we examined the GDGT concentration in forty sediment samples from geothermal hot springs in the Great Basin (USA). Sediment samples were collected in tandem with extensive geochemical and site characterization. Hot spring temperatures ranged from 31 to 95°C and pH values from 6.8 to 10.7. Parametric Pearson's correlation coefficients and nonparametric Spearman's rho values were calculated to identify significant correlations between GDGT profiles and geochemical analytes. Isoprenoidal GDGTs (iGDGTs) negatively correlated with pH and positively …

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