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Full-Text Articles in Microbiology
Bioinformatic And Sequence Analysis Of Four Resuscitation Promoting Factor (Rpf) Gene Homologues In Mycobacterium Avium Subsp. Paratuberculosis (Mpt), And Expression Of The Putative Mpt Rpfb In Escherichia Coli., David Dale Hedlund
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Mycobacterium avium subsp. paratuberculosis (Mpt), the causative agent of Johne's disease (JD), is a global problem in the agricultural industry. It is estimated that 25% of all U.S. dairy herds are JD positive. One obstacle in the management of JD is the lack a sensitive diagnostic test for use during the early stages of infection. Resuscitation promoting factors (Rpf) are proteins that promote the growth of many species of Actinobacteria. If Rpf proteins could enhance the growth of Mpt, the sensitivity of diagnostic fecal culture could be improved, and the impact of JD on the dairy industry would be significantly …