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Full-Text Articles in Microbiology
Development Of An In Vitro Culture System For Cryptosporidium Parvum, Georgia Wilke
Development Of An In Vitro Culture System For Cryptosporidium Parvum, Georgia Wilke
Arts & Sciences Electronic Theses and Dissertations
Cryptosporidium is a genus of protozoan parasites that causes diarrheal disease in humans and other animals. There are two major species that cause disease in humans: C. parvum, which infects both humans and animals, and C. hominis, which primarily infects humans. A recent study investigating the etiologies of pediatric diarrheal illness in Africa and South Asia found that Cryptosporidium is the 2nd most prevalent cause of diarrhea in infants and may be a contributing factor to chronic malnutrition. This discovery has led to renewed interest in studying this parasite and a reexamination of the barriers to studying Cryptosporidium. The main …
Ancient Bacteria–Amoeba Relationships And Pathogenic Animal Bacteria, Joan E. Strassmann, Longfei Shu
Ancient Bacteria–Amoeba Relationships And Pathogenic Animal Bacteria, Joan E. Strassmann, Longfei Shu
Biology Faculty Publications & Presentations
Long before bacteria infected humans, they infected amoebas, which remain a potentially important reservoir for human disease. Diverse soil amoebas including Dictyostelium and Acanthamoeba can host intracellular bacteria. Though the internal environment of free-living amoebas is similar in many ways to that of mammalian macrophages, they differ in a number of important ways, including temperature. A new study in PLOS Biology by Taylor-Mulneix et al. demonstrates that Bordetella bronchiseptica has two different gene suites that are activated depending on whether the bacterium finds itself in a hot mammalian or cool amoeba host environment. This study specifically shows that B. …