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Full-Text Articles in Microbiology
Analysis Of Genes Involved In Anaerobic Growth In Porphyromonas Gingivalis And Shewanella Oneidensis Mr-1, Dilini Sanjeevi Kumarasinghe
Analysis Of Genes Involved In Anaerobic Growth In Porphyromonas Gingivalis And Shewanella Oneidensis Mr-1, Dilini Sanjeevi Kumarasinghe
Theses and Dissertations
Porphyromonas gingivalis is an oral Gram-negative anaerobic bacterium implicated in periodontal disease, a polymicrobial inflammatory disease that is correlated with cardiovascular disease, diabetes and preterm birth. Therefore understanding the physiology and metabolism of P.gingivalis through genetic manipulation is important in identifying mechanisms to eliminate this pathogen. Although numerous genetic tools have been developed for the manipulation of other bacterial species, they either do not function in P.gingivalis or they have limitations. We modified a Mariner transposon pHimarEM1 system that was developed for Flavobacterium johnsoniae for mutagenesis of P. gingivalisWe introduced the P. gingivalis fimA promoter upstream of the transposase …
Viral Hemorrhagic Septicemia Virus (Vhsv) Great Lakes Strain Ivb: Viral Detection, Mechanisms Of Infection, And Host-Virus Interactions In The Yellow Perch (Perca Flavescens), Wendy Joy Olson
Theses and Dissertations
Viral hemorrhagic septicemia virus (VHSV) is one of the most devastating and problematic viral fish diseases to plague the European aquaculture industry, and due to its pathogenicity, disease course, mortality rates, and wide host range, remains one of the most pathogenic viral diseases of finfish worldwide. A new freshwater strain of viral hemorrhagic septicemia virus IVb (VHSV-IVb) in the Great Lakes has been found capable of infecting a wide number of naive species, and has been associated with large fish kills in the Midwestern United States since its discovery in 2005. In this study, the yellow perch, Perca flavescence, one …