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Full-Text Articles in Exercise Science
The Effects Of Resistance Exercise Training On Insulin Resistance Development In Female Rodents With Type 1 Diabetes, Mitchell James Sammut
The Effects Of Resistance Exercise Training On Insulin Resistance Development In Female Rodents With Type 1 Diabetes, Mitchell James Sammut
Electronic Thesis and Dissertation Repository
The etiology of insulin resistance (IR) development in type 1 diabetes mellitus (T1DM) remains unclear; however, impaired skeletal muscle metabolism may play a role. While IR development has been established in male T1DM rodents, female rodents have yet to be examined in this context. Resistance exercise training (RT) has been shown to improve IR and is associated with a lower risk of hypoglycemia onset in T1DM compared to aerobic exercise. Additionally, the molecular mechanisms mediating RT-induced improvements in insulin sensitivity remain unclear. Therefore, the purpose of this study was to investigate the effects of RT on IR development in female …
Post-Activation Potentiation Induced By Concentric Contractions At Three Speeds In Humans, Alexander Zero
Post-Activation Potentiation Induced By Concentric Contractions At Three Speeds In Humans, Alexander Zero
Electronic Thesis and Dissertation Repository
Post-activation potentiation (PAP) is the acute enhancement of contractile properties following a short duration (<10s) high intensity contraction. Compared with isometric contractions, little is known about the PAP response induced by concentric conditioning contractions (CCs) and the effect of contractile speeds. In the dorsiflexors of 10 participants, twitch responses were measured following 5s of maximal effort concentric CCs at each of 10, 20 and 50°/s. Concentric PAP responses were compared to a maximal isometric voluntary contraction (MVC) matched for contraction time. Additionally, concentric CCs were compared to isometric CCs matched for mean torque, contraction area and time. The principal finding was that the PAP response following maximal concentric CCs was independent of contractile speed and, there was no difference in the PAP response between concentric CCs and an isometric MVC. Maximal contractions, regardless of contraction modality, likely produce sufficient Ca2+ to induce a full PAP response, and thus there was no difference between speeds or contraction type. Concentric CCs had significantly larger peak twitch torque than their isometric torque matches (49-58%), and faster maximal rates of torque development at the three speeds (62-77%). However, these responses are likely related to greater muscle activation (EMG), and not contraction modality per se. Thus, PAP responses following maximal concentric CCs are not affected by velocity and responses are not different from an isometric MVC. This indicates maximal …
The Effects Of Exercise Training Versus Intensive Insulin Treatment On Skeletal Muscle Fibre Content In Type 1 Diabetes Mellitus Rodents, David P. Mcbey
The Effects Of Exercise Training Versus Intensive Insulin Treatment On Skeletal Muscle Fibre Content In Type 1 Diabetes Mellitus Rodents, David P. Mcbey
Electronic Thesis and Dissertation Repository
In patients with Type I diabetes mellitus (T1DM) undergoing intensive insulin therapy, the development of insulin resistance (IR) is linked to the improper storage of intramyocellular lipid (IMCL) species. While both IR and IMCL are improved with combined aerobic and resistance training, it is unclear how these adaptations relate to individual fibre-type transitions and metabolic function. This study aimed to compare the effects of combined exercise training versus conventional and intensive insulin therapy on skeletal muscle fibres in T1DM rodents. Seventeen Sprague-Dawley rats were divided into groups: Control-Sedentary (CS; n=4), conventionally-treated T1DM sedentary (DCT; n=4), intensively-treated T1DM sedentary (DIT; n=5) …