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Full-Text Articles in Exercise Science
The Neuroprotective Effects Of Endurance Training On The Aging Brain, Katelyn Norton
The Neuroprotective Effects Of Endurance Training On The Aging Brain, Katelyn Norton
Electronic Thesis and Dissertation Repository
Dysregulation of autonomic control often develops with advancing age, favoring a chronic state of heightened sympathetic outflow with parasympathetic withdrawal. However, the mechanisms of this age-related autonomic impairment are not known and may relate to alterations in brain structure (e.g. cortical atrophy) and/or altered neural function, particularly in regions related to the cortical autonomic network, namely, the medial prefrontal cortex (MPFC), insula cortex (IC), and hippocampus (HC). Exercise exerts beneficial effects on brain structure and, in the case of cognition, neurologic function; however, how exercise affects regions of the brain related to autonomic function are not known. This thesis tested …
Neuroprotective Effects Of Long-Term Endurance Training On The Cortical Autonomic Network In The Aging Brain, Torri A. Luchyshyn
Neuroprotective Effects Of Long-Term Endurance Training On The Cortical Autonomic Network In The Aging Brain, Torri A. Luchyshyn
Electronic Thesis and Dissertation Repository
This study tested whether long-term endurance training in older adults (ET; n = 15, 55 ± 4 years, relative VO2max = 50 ± 8 ml/kg/min) would alter cardiovagal control and preserve the cortical autonomic network compared to age-matched controls (CON; n = 15, 56 ± 4 years, relative VO2max = 37 ± 9 ml/kg/min). The hypothesis predicts 1) altered deactivation patterns of the ventral medial prefrontal cortex (vMPFC) in response to isometric hand grip (IHG) and 2) greater indices of cardiovagal control; a) increased baroreflex sensitivity at rest, b) greater heart rate change (ΔHR) and c) …