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Full-Text Articles in Exercise Science
The Neuroprotective Effects Of Endurance Training On The Aging Brain, Katelyn Norton
The Neuroprotective Effects Of Endurance Training On The Aging Brain, Katelyn Norton
Electronic Thesis and Dissertation Repository
Dysregulation of autonomic control often develops with advancing age, favoring a chronic state of heightened sympathetic outflow with parasympathetic withdrawal. However, the mechanisms of this age-related autonomic impairment are not known and may relate to alterations in brain structure (e.g. cortical atrophy) and/or altered neural function, particularly in regions related to the cortical autonomic network, namely, the medial prefrontal cortex (MPFC), insula cortex (IC), and hippocampus (HC). Exercise exerts beneficial effects on brain structure and, in the case of cognition, neurologic function; however, how exercise affects regions of the brain related to autonomic function are not known. This thesis tested …
Assessing Multi-Unit Muscle Sympathetic Nerve Activity Across Groups: A Multivariate Approach To A Multivariate Concept, Danielle N. Brewer
Assessing Multi-Unit Muscle Sympathetic Nerve Activity Across Groups: A Multivariate Approach To A Multivariate Concept, Danielle N. Brewer
Electronic Thesis and Dissertation Repository
Baseline muscle sympathetic nerve activity (MSNA) comparisons of age (young & old, n=40) and cardiovascular disease (CVD) state (young: Y, old: O, metabolic syndrome: MET, coronary artery disease: CAD, chronic heart failure: CHF, n= 36) groups were made to assess which MSNA variable(s) best describe group differences using a MANOVA-based approach across 10 variables. The hypothesis that action potential (AP) variables would better discriminate between groups than integrated variables was not supported. Burst frequency and incidence together significantly differentiated between groups with variability attributed to spikes/min and spikes/100hb removed. Significant group differences were noted for these variables such that Y