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Full-Text Articles in Exercise Science
Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii
Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii
Doctoral Dissertations
Muscle size does not fully explain variations in muscle strength. Fat content has been implicated in muscle weakness, though this relationship remains unclear. The relationship between fat and strength may vary between scales (e.g., cellular, organ, and organism). The goal of this dissertation was to clarify the role of fat in the structure and function of muscle using in vitro and in vivo techniques across multiple scales in adults 21-45 years old. Study 1 tested the agreement of intramyocellular lipid (IMCL) content between oil red o (ORO) and magnetic resonance spectroscopy (MRS) techniques. These measures of IMCL were also compared …
Lower Extremity Muscle Contributions To Acl Loading In Healthy And Acl-Reconstructed Females, Shelby Peel
Lower Extremity Muscle Contributions To Acl Loading In Healthy And Acl-Reconstructed Females, Shelby Peel
Doctoral Dissertations
Females are 16 times greater to sustain a second ACL injury compared to their healthy female counterparts. Many of these females return to play their respective sport after an ACL-reconstruction (ACLR). However, little is known about the influence fatigue in sport has on lower extremity mechanics of ACLR females. The purpose of this study was to investigate the influence muscular fatigue may have on lower extremity mechanics in healthy and ACLR females. It was hypothesized that 1) healthy control and ACLR females would demonstrate different hip, knee, and ankle mechanics, regardless of fatigue, 2) fatigue would influence hip, knee, and …
Mechanisms That Limit Oxidative Phosphorylation During High-Intensity Muscle Contractions In Vivo, Miles F. Bartlett
Mechanisms That Limit Oxidative Phosphorylation During High-Intensity Muscle Contractions In Vivo, Miles F. Bartlett
Doctoral Dissertations
Skeletal muscle oxidative capacity plays a critical role in human health and disease. Although current models of oxidative phosphorylation sufficiently describe skeletal muscle energetics during moderate-intensity contractions, much is still unknown about the mechanisms that control and limit oxidative phosphorylation during high-intensity contractions. In particular, the oxygen cost of force generation is augmented during exercise at workloads above the lactate threshold. Presently, it is unclear whether this augmentation in muscle oxygen consumption is driven by increased rates of oxidative ATP synthesis (ATPOX) or by decreases in the efficiency of ATPOX due to mitochondrial uncoupling. To address this …
Changes In Muscle Control And Coordination In Novel Task Learning, Sangsoo Park
Changes In Muscle Control And Coordination In Novel Task Learning, Sangsoo Park
Doctoral Dissertations
Learning many daily life motor skills is critical for survival and the quality of living in humans. As children, we develop walking and running patterns to move the body from point A to B without falling, and we learn to grasp a wide variety of objects during activities of daily living. Motor skills can be properly performed by appropriate muscle activations which are controlled by the central nervous system. How does the central nervous system develop and fine-tune its control strategy to learn a new motor skill? The aim of this dissertation was to better understand how human participants alter …