Exercise Science Commons^™

Pkd1 Inhibits Ampk2 Through Phosphorylation Of Serine 491 And Impairs Insulin Signaling In Skeletal Muscle Cells, Kimberly A. Coughlan, Rudy J. Valentine, Bella S. Sudit, Katherine Allen, Yossi Dagon, Barbara B. Kahn, Neil B. Ruderman, Asish K. Saha

Rudy Valentine

Background: Diminished activity of the enzyme AMP-activated protein kinase (AMPK) is associated with impaired insulin signaling.

Results: Protein Kinase (PK)C/D1 activation inhibits AMPK2 via Ser491 phosphorylation; PKD1 inhibition prevents this in skeletal muscle cells.

Conclusion: PKD1 is a novel upstream AMPK-kinase that phosphorylates AMPK on Ser491 and regulates insulin signaling.

Significance: PKD1 inhibition may be a novel strategy for improving insulin sensitivity.

Nutrient Excess And Ampk Downregulation In Incubated Skeletal Muscle And Muscle Of Glucose Infused Rats, Kimberly A. Coughlan, Thomas W. Balon, Rudy J. Valentine, Robert Petrocelli, Vera Schultz, Amana Brandon, Gregory J. Cooney, Edward W. Kraegen, Neil B. Ruderman, Asish K. Saha

Rudy Valentine

We have previously shown that incubation for 1h with excess glucose or leucine causes insulin resistance in rat extensor digitorum longus (EDL) muscle by inhibiting AMP-activated protein kinase (AMPK). To examine the events that precede and follow these changes, studies were performed in rat EDL incubated with elevated levels of glucose or leucine for 30min-2h. Incubation in high glucose (25mM) or leucine (100μM) significantly diminished AMPK activity by 50% within 30min, with further decreases occurring at 1 and 2h. The initial decrease in activity at 30min coincided with a significant increase in muscle glycogen. The subsequent decreases at 1h were …

Imoxin Attenuates Lps‐Induced Inflammation And Murf1 Expression In Mouse Skeletal Muscle, Rudy J. Valentine, Matthew A. Jefferson, Marian L. Kohut, Hyeyoon Eo

Rudy Valentine

The double‐stranded RNA‐dependent protein kinase (PKR) contributes to inflammatory cytokine expression and disease pathogenesis in many conditions. Limited data are available on the efficacy of the PKR inhibitor imoxin to prevent lipopolysaccharide (LPS)‐induced inflammation in skeletal muscle in vivo. The aim of this study was to evaluate the effect of imoxin, a PKR inhibitor, on inflammatory and atrophy signaling in skeletal muscle in response to an acute inflammatory insult with LPS. Six‐week old C57BL/6J mice received vehicle (saline) or 0.5 mg/kg imoxin 24 and 2 h prior to induction of inflammation via 1 mg/kg LPS. Gastrocnemius muscles were collected 24 …

A Single High‐Fat Meal Alters Human Soluble Rage Profiles And Pbmc Rage Expression With No Effect Of Prior Aerobic Exercise, Kelly N.Z. Fuller, Rudy J. Valentine, Edwin R. Miranda, Prabhakaran Kumar, Bellur S. Prabhakar, Jacob M. Haus

Rudy Valentine

A high‐fat diet can induce inflammation and metabolic diseases such as diabetes and atherosclerosis. The receptor for advanced glycation endproducts (RAGE) plays a critical role in metabolic disease pathophysiology and the soluble form of the receptor (sRAGE) can mitigate these effects. However, little is known about RAGE in the postprandial condition and the effect of exercise in this context. Thus, we aimed to determine the effects of a single high‐fat meal (HFM) with and without prior exercise on peripheral blood mononuclear cell (PBMC) RAGE biology. Healthy males (n = 12) consumed a HFM on two occasions, one without prior …

Effects Of Lower Extremity Aerobic Exercise And Conditioned Pain Modulation On Evoked Shoulder Pain, Logan Lumpkins, Craig Wassinger Pt, Ph. D

Logan Lumpkins

Greater Polar Moment Of Inertia At The Tibia In Athletes Who Develop Stress Fractures, Lee A. Weidauer, Teresa Binkley, Matthew Vukovich, Bonny Specker

Matthew Vukovich

Background: Several previous investigations have determined potential risk factors for stress fractures in athletes and military personnel. Purpose: To determine factors associated with the development of stress fractures in female athletes. Study Design: Case-control study; Level of evidence, 3. Methods: A total of 88 female athletes (cross-country, n ¼ 29; soccer, n ¼ 15; swimming, n ¼ 9; track and field, n ¼ 14; volleyball, n ¼ 12; and basketball, n ¼ 9) aged 18 to 24 years were recruited to participate in a longitudinal bone study and had their left distal tibia at the 4%, 20%, and 66% sites …

Disaggregating The Relative Influence Of Genetic, Environmental And Individual Factors On Lcl And Hdl Cholesterols And Bmi For A Sample Of African American (Aa) Mothers And Daughters, C. Jayne Brahler, Jewel Harden, Michelle Mchone, Matthew Soules, Eric Evans, Ann Alyanak, Fred Diakpieng, Paul M. Vanderburgh

Paul M. Vanderburgh

There are many reports about the associations between blood lipids, body mass index (BMI) and dietary cholesterol intakes both within the individual and between related individuals. The purpose of this descriptive research project was to investigate the relationships between LDL and HDL cholesterols, body mass index and dietary cholesterol intakes for a sample of African American (AA) mothers and their daughters and to attempt to separate the contribution of genetic versus environmental factors. Mother and daughter participants (n =42 and 66, respectively) were 12-14-hours fasted when blood samples were drawn, heights and weights measured, and 24 hour food recalls completed.

Physical Screening And Testing: From Purpose To Research To Application, Rob Orr

Rob Marc Orr

Session Objectives:

•Discuss the purposes of different physical assessments

•Designing measures useful for assessing tactical personnel

•Applying assessments in the field

Exploring The Utilisation Of Stand Up Paddle Boarding In Australia, Ben Schram, James Furness

James Furness

Stand Up Paddle Boarding (SUP) has grown exponentially in the last few years with unprecedented participation rates globally. Despite some scientific research on physiological and performance variables, minimal information exists regarding participation and utilisation. The purpose of this study was to discover more about how and where people participate in the relatively new sport of SUP. An open-source online survey application was administered internationally to active SUP participants to capture information relevant to both demographics and participation. Of a total of 240 responses, 154 (64.2%) were Australian. The average SUP rider was 42.9 ± 11.7 years, mass 80.4 ± 18.7 …

Exploring The Utilisation Of Stand Up Paddle Boarding In Australia, Ben Schram, James Furness

Ben Schram

Stand Up Paddle Boarding (SUP) has grown exponentially in the last few years with unprecedented participation rates globally. Despite some scientific research on physiological and performance variables, minimal information exists regarding participation and utilisation. The purpose of this study was to discover more about how and where people participate in the relatively new sport of SUP. An open-source online survey application was administered internationally to active SUP participants to capture information relevant to both demographics and participation. Of a total of 240 responses, 154 (64.2%) were Australian. The average SUP rider was 42.9 ± 11.7 years, mass 80.4 ± 18.7 …

Epidemiology Of Injuries In Stand-Up Paddle Boarding, James Furness, Olayinka Olorunnife, Ben Schram, Michael Climstein, Wayne Hing

Ben Schram

Background: Stand-up paddle boarding (SUP) is a recreational activity and sport that has grown exponentially, with participation increasing from 1.1 million in 2010 to 2.8 million in 2014 in the United States alone. Despite this growth in participation, SUP remains underresearched with regard to injury epidemiology. Purpose: To investigate injury epidemiology (severity, location, type, mechanism) in SUP.Study Design:Descriptive epidemiology study. Methods: An open-source online survey was administered to active SUP participants internationally. The survey captured information relevant to demographics, participation, and injury history over the past 12 months. Results: Of 240 participants included in the data analysis, 67.1% were males, …

Epidemiology Of Injuries In Stand-Up Paddle Boarding, James Furness, Olayinka Olorunnife, Ben Schram, Michael Climstein, Wayne Hing

Wayne Hing

Background:

Stand-up paddle boarding (SUP) is a recreational activity and sport that has grown exponentially, with participation increasing from 1.1 million in 2010 to 2.8 million in 2014 in the United States alone. Despite this growth in participation, SUP remains underresearched with regard to injury epidemiology.

Purpose:

To investigate injury epidemiology (severity, location, type, mechanism) in SUP.Study Design:Descriptive epidemiology study.

Methods:

An open-source online survey was administered to active SUP participants internationally. The survey captured information relevant to demographics, participation, and injury history over the past 12 months.

Results:

Of 240 participants included in the data analysis, 67.1% were males, …

Prevalence, Predictors And Benefits Of Resistance Training For Improving Gait Speed In Aged Care, Justin Keogh, Timothy Henwood, Hugh Senior, Samantha Fien

Justin Keogh

No abstract provided.

Prevalence, Consequences And Effects Of Exercise On Sarcopenia In Aged Care, Justin Keogh, Timothy Henwood, Hugh Senior, Jennifer Hewitt

Justin Keogh

No abstract provided.

Effects Of Water-Based Exercise On Bone Health Of Middle-Aged And Older Adults: A Systematic Review And Meta-Analysis, Vini Simas, Wayne Hing, Rodney Pope, Mike Climstein

Rodney P Pope

BACKGROUND: Age-related bone loss is a major health concern. Only exercises associated with high-impact and mechanical loading have been linked to a positive effect on bone turnover; however, these types of exercises may not always be appropriate for middle-aged and older adults due to physical decline or chronic disorders such as osteoarthritis. Water-based exercise (WBE) has been shown to affect different components of physical fitness, has lower risks of traumatic fracture, and applies less stress to joints. However, the effects of WBE on bone health are unclear. OBJECTIVE: This study aimed to explore whether WBE is effective in preventing age-related …

Effects Of Water-Based Exercise On Bone Health Of Middle-Aged And Older Adults: A Systematic Review And Meta-Analysis, Vini Simas, Wayne Hing, Rodney Pope, Mike Climstein

Wayne Hing

BACKGROUND: Age-related bone loss is a major health concern. Only exercises associated with high-impact and mechanical loading have been linked to a positive effect on bone turnover; however, these types of exercises may not always be appropriate for middle-aged and older adults due to physical decline or chronic disorders such as osteoarthritis. Water-based exercise (WBE) has been shown to affect different components of physical fitness, has lower risks of traumatic fracture, and applies less stress to joints. However, the effects of WBE on bone health are unclear. OBJECTIVE: This study aimed to explore whether WBE is effective in preventing age-related …

The Effect Of Previous Wingate Performance Using One Body Region On Subsequent Wingate Performance Using A Different Body Region, Leonie Harvey, Matthew Bousson, Chris Mclellan, Dale Lovell

Chris McLellan

The 30 second Wingate Anaerobic Test (WAnT) is the gold standard measure of anaerobic performance. The present investigation aimed to determine if a previous WAnT using one body region significantly affected a subsequent WAnT using a different body region. Twelve male university students (n = 12, 23 ± 2 years, 84 ± 16.1 kg, 178.5 ± 7.4 cm) volunteered to complete two repeated WAnT protocols (either lower body WAnT followed by an upper body WAnT or vice versa) on two separate testing occasions. The upper body WAnT was conducted on a modified electromagnetically braked cycle ergometer using a flywheel braking …

The Association Between Fundamental Athletic Movements And Physical Fitness In Elite Junior Australian Footballers, Carl Woods, Ian Mckeown, Justin Keogh, Sam Robertson

Justin Keogh

The Physiological, Musculoskeletal And Psychological Effects Of Stand Up Paddle Boarding, Ben Schram, Wayne F. Hing, Michael Climstein

Wayne Hing

Background: Stand up paddle boarding (SUP) is a rapidly growing sport and recreational activity where anecdotal evidence exists for its proposed health, fitness and injury rehabilitation benefits. While limited scientific evidence exists to substantiate these claims, previous studies have shown that high levels of fitness, strength and balance exists amongst participants of this sport. The purpose of this study was to conduct a training intervention on a group of previously untrained individuals to ascertain the potential of SUP on various health parameters. Methods: An intervention study was conducted where after being tested initially, subjects were left for 6 weeks to …

The Physiological, Musculoskeletal And Psychological Effects Of Stand Up Paddle Boarding, Ben Schram, Wayne F. Hing, Michael Climstein

Ben Schram

Background: Stand up paddle boarding (SUP) is a rapidly growing sport and recreational activity where anecdotal evidence exists for its proposed health, fitness and injury rehabilitation benefits. While limited scientific evidence exists to substantiate these claims, previous studies have shown that high levels of fitness, strength and balance exists amongst participants of this sport. The purpose of this study was to conduct a training intervention on a group of previously untrained individuals to ascertain the potential of SUP on various health parameters. Methods: An intervention study was conducted where after being tested initially, subjects were left for 6 weeks to …

Strength Training For Plantar Fasciitis And The Intrinsic Foot Musculature: A Systematic Review., Dean Huffer, Wayne Hing, Richard Newton, Mike Clair

Wayne Hing

The aim was to critically evaluate the literature investigating strength training interventions in the treatment of plantar fasciitis and improving intrinsic foot musculature strength. A search of PubMed, CINHAL, Web of Science, SPORTSDiscus, EBSCO Academic Search Complete and PEDRO using the search terms plantar fasciitis, strength, strengthening, resistance training, intrinsic flexor foot, resistance training. Seven articles met the eligibility criteria. Methodological quality was assessed using the modified Downs and Black checklist. All articles showed moderate to high quality, however external validity was low. A comparison of the interventions highlights significant differences in strength training approaches to treating plantar fasciitis and …

The Physiological Profile Of Male Competitive And Recreational Surfers, James Furness, Wayne Hing, Jeremy M Sheppard, Sean Newcomer, Ben Schram, Mike Climstein

Ben Schram

Surfing consists of both high and low intensity paddling of varying durations, utilizing both the aerobic and anaerobic systems. Surf specific physiological studies lack adequate group sample sizes and VO2peak values are yet to determine differences between competitive and recreational surfers. The purpose of this study was therefore to provide a comprehensive physiological profile of both recreational and competitive surfers. This multi-site study involved 62 male surfers, recreational (n = 47) and competitive (n = 15). Anthropometric measurements were conducted followed by DEXA, anaerobic testing and finally aerobic testing. VO2peak was significantly greater in competitive compared to recreational surfers (M …

Load Carriage And What It Means For Search & Rescue, Rob M. Orr, Rodney Pope

Rob Marc Orr

SAR personnel may often be required to carry external loads as a task requirement. In turn these external loads may be carried in extreme environments across unpredictable terrain. In tactical occupations, like those undertaken by Defence Force, law enforcement and fire and rescue personnel, these loads, which can range from 10 to over 50kg, are known to cause a variety of injuries to the neurological and musculoskeletal systems of the carrier. In addition, these loads are known to impede task performance and in some cases have ultimately led to mission failure. To mitigate these potential risks of injury and performance …

Using Mixed Methods To Measure The Perception Of Community Capacity In An Academic–Community Partnership For A Walking Intervention, Charkarra Anderson-Lewis, Diana Castellanos, Arnecca Byrd, Karen Zynda, Alicia Sample, Vickie Reed, Mary Beard, Latessa Minor, Kathleen Yadrick

Diana Cuy Castellanos

H.U.B. City Steps is a 5-year community-based participatory research walking intervention designed to help lower blood pressure in a majority African American population in southern Mississippi via community collaboration and capacity building, increased walking, culturally tailored health education sessions, and motivational interviewing. Building community capacity for physical activity is a key component of this intervention. Qualitative and quantitative methods have been used to assess how project stakeholders perceive the community capacity-building efforts of the project. This article illustrates the baseline results of this mixed methods approach from the perspective of three groups of stakeholders: project researchers and staff, community advisory …

Acute Effects Of Whole-Body Vibration On Lower Extremity Muscle Performance In Persons With Multiple Sclerosis, Kurt Jackson, Harold Merriman, Paul Vanderburgh, C. Brahler

C. Jayne Brahler

Background and Purpose: Whole-body vibration (WBV) is a relatively new form of exercise training that may influence muscle performance. This study investigated the acute effects of high (26 Hz) and low (2 Hz) frequency WBV on isometric muscle torque of the quadriceps and hamstrings in persons with multiple sclerosis (MS).

Participants and Method: Fifteen individuals (mean age = 54.6 years, SD = 9.6) with MS and Expanded Disability Status Scale (EDSS) scores ranging from 0-6.5 (mean = 4.2, SD = 2.3) participated in this randomized cross-over study. Following baseline measures of isometric quadricep and hamstring torque, subjects were exposed to …

Practical Applications Of Biomechanical Principles In Resistance Training: The Use Of Bands And Chains, Paul A. Swinton, Justin Keogh, Jason Lake

Justin Keogh

In recent years, it has become popular for athletes and recreational trainers to perform resistance training with the addition of bands and chains. In this paper, we consider the advantages of manipulating an exercise to match the resistance provided with the force capabilities of the lifter, which generally change throughout the movement. We explain that bands and chains can be used to manipulate a variety of exercises that have the potential to enhance performance in sport and in many daily tasks. Whilst there are many similaritiesbetween the use of bands and chains for resistance training, we note that there are …

Australian Soldier Load Carriage: From Gallipoli To Afghanistan, Rob Orr

Rob Marc Orr

Background: •From the early Assyrian spearman of antiquity (circa 800 B.C.), soldiers have been required to carry external loads consisting of weaponry, equipment and food (Orr, 2010; Knapicket al., 2012:2004) •Downstream effects of these loads have been shown to impact on the tactics of warfare, cause injury and reduce fighting force size (Lee, 2007; Breen, 2002;Lothian , 1921)

The Impact Of Two Different Conditioning Programs On Fitness Characteristics Of Police Academy Cadets, Charles Cocke, Jay Dawes, Rob Orr

Rob Marc Orr

Abstract published in the Journal of Science and Medicine in Sport – Supplement, 18(6), pp. 98. Access the abstract

Australian Army Recruit Training: Course Length And Recruit Injury Rates, Georgina Dawson, Ryan Broad, Rob Orr

Rob Marc Orr

Access abstract in the Conference Abstract E-book, page 115

Load Carriage Distance Run And Pushups Tests: No Body Mass Bias And Occupationally Relevant, Paul M. Vanderburgh, Nicholas S. Mickley, Philip A. Anloague, Kimber Lucius

Philip A. Anloague

Recent research has demonstrated body mass (M) bias in military physical fi tness tests favoring lighter, not just leaner, service members. Mathematical modeling predicts that a distance run carrying a backpack of 30 lbs would eliminate M-bias. The purpose of this study was to empirically test this prediction for the U.S. Army push-ups and 2-mile run tests. Two tests were performed for both events for each of 56 university Reserve Offi cer Training Corps male cadets: with (loaded) and without backpack (unloaded). Results indicated signifi cant M-bias in the unloaded and no M-bias in the loaded condition for both events. …