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Medical Sciences

Doctoral Dissertations

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Full-Text Articles in Exercise Science

Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii Aug 2023

Role Of Fat Content On The Structure And Function Of Human Skeletal Muscle, Joseph A. Gordon Iii

Doctoral Dissertations

Muscle size does not fully explain variations in muscle strength. Fat content has been implicated in muscle weakness, though this relationship remains unclear. The relationship between fat and strength may vary between scales (e.g., cellular, organ, and organism). The goal of this dissertation was to clarify the role of fat in the structure and function of muscle using in vitro and in vivo techniques across multiple scales in adults 21-45 years old. Study 1 tested the agreement of intramyocellular lipid (IMCL) content between oil red o (ORO) and magnetic resonance spectroscopy (MRS) techniques. These measures of IMCL were also compared …


Changes In Muscle Control And Coordination In Novel Task Learning, Sangsoo Park Mar 2019

Changes In Muscle Control And Coordination In Novel Task Learning, Sangsoo Park

Doctoral Dissertations

Learning many daily life motor skills is critical for survival and the quality of living in humans. As children, we develop walking and running patterns to move the body from point A to B without falling, and we learn to grasp a wide variety of objects during activities of daily living. Motor skills can be properly performed by appropriate muscle activations which are controlled by the central nervous system. How does the central nervous system develop and fine-tune its control strategy to learn a new motor skill? The aim of this dissertation was to better understand how human participants alter …