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Full-Text Articles in Kinesiology

Effects Of Dietary Nitrate And Caffeine On End Power And Work Above End Power During A 3 Min All-Out Test In Trained Male Cyclists, Anthony M. Hagele, Kyle Sunderland, Petey W. Mumford, Chad Kerksick May 2026

Effects Of Dietary Nitrate And Caffeine On End Power And Work Above End Power During A 3 Min All-Out Test In Trained Male Cyclists, Anthony M. Hagele, Kyle Sunderland, Petey W. Mumford, Chad Kerksick

Faculty Scholarship

Background: The purpose of this study was to examine the effects of acute dietary nitrate (NO3−) and caffeine (CAF) supplementation on end power (EP) and work performed above EP (WEP) in trained male cyclists during a 3 min all-out test (3MT) on a cycle ergometer.

Methods: Fifteen healthy, trained male cyclists (28.5 ± 5.3 years, 79.2 ± 9.1 kg, VO2peak 55.2 ± 5.6 mL·kg−1·min−1) completed four exercise trials in a randomized, double-blind, placebo-controlled, crossover study design separated by 3–7 days. The four experimental conditions were placebo beverage (nitrate-depleted) + placebo capsule, nitrate-rich beetroot juice + placebo capsule (BR), …


Effects Of A Carbohydrate + Caffeine Beverage On Game Performance, Blood Glucose And Perceived Effort In Collegiate Women Soccer Players, Andrew Jagim, Abby Ambrosius, Makenna Carpenter, Joesi Krieger, Lochlan Charley, Jennifer Fields, Margaret T. Jones, Chad Kerksick Feb 2026

Effects Of A Carbohydrate + Caffeine Beverage On Game Performance, Blood Glucose And Perceived Effort In Collegiate Women Soccer Players, Andrew Jagim, Abby Ambrosius, Makenna Carpenter, Joesi Krieger, Lochlan Charley, Jennifer Fields, Margaret T. Jones, Chad Kerksick

Faculty Scholarship

Carbohydrate availability and caffeine ingestion have been shown to elicit improvements in performance independently of one another. The purpose of the study was to examine the effect of a carbohydrate + caffeine beverage on performance and perceived effort in soccer players. Forty-three collegiate women’s soccer athletes were recruited to participate during a single day of simulated match play, in which each team played once. Athletes consumed either a carbohydrate + caffeine (Experimental) beverage or a control (Control) beverage (flavored water) during half-time in a double-blind, placebo-controlled, randomized control trial design. Prior to and after each game, Ratings of Perceived Exertion …


International Society Of Sports Nutrition Position Stand: Effects Of Dietary Antioxidants On Exercise And Sports Performance, Drew E. Gonzalez, Broderick L. Dickerson, Brandon M. Roberts, Jennifer A. Kurtz, Hunter S. Waldman, Adam M. Gonzalez, Matthew J. Mcallister, Jeffery L. Heileson, Richard J. Bloomer, Shawn M. Arent, Darren G. Candow, Jeffrey R. Stout, Karen A. Hecht, Bill Campbell, Chad Kerksick, Douglas Kalman, Jose Antonio, Richard B. Kreider Feb 2026

International Society Of Sports Nutrition Position Stand: Effects Of Dietary Antioxidants On Exercise And Sports Performance, Drew E. Gonzalez, Broderick L. Dickerson, Brandon M. Roberts, Jennifer A. Kurtz, Hunter S. Waldman, Adam M. Gonzalez, Matthew J. Mcallister, Jeffery L. Heileson, Richard J. Bloomer, Shawn M. Arent, Darren G. Candow, Jeffrey R. Stout, Karen A. Hecht, Bill Campbell, Chad Kerksick, Douglas Kalman, Jose Antonio, Richard B. Kreider

Faculty Scholarship

Following a comprehensive review, the International Society of Sports Nutrition (ISSN) has developed an official position on the role of dietary antioxidants in exercise and sport. Antioxidants play a complex, context-dependent role in vivo; they can facilitate recovery from exercise but may also hinder training adaptations when consumed at supraphysiological doses. While endogenous antioxidant systems can effectively maintain redox balance, dietary sources, particularly whole foods, can help mitigate excessive oxidative stress following intense/heavy training or inadequate recovery. The influence of dietary antioxidants depend on timing, dosage, type, and individual factors. The ISSN’s official position encompasses the following: (1) Redox balance …


Reliability Of Vertical Jump Force-Time Metrics In Collegiate Athletes Compared To Recreationally Active Individuals, Dimitrije Cabarkapa, Robert Smith, Luke Chowning, Tyler Neltner, Quincy R. Johnson, Yang Yang, Thayne A. Munce Nov 2025

Reliability Of Vertical Jump Force-Time Metrics In Collegiate Athletes Compared To Recreationally Active Individuals, Dimitrije Cabarkapa, Robert Smith, Luke Chowning, Tyler Neltner, Quincy R. Johnson, Yang Yang, Thayne A. Munce

Faculty Scholarship

As neuromuscular performance assessment has become a fundamental component of athlete monitoring, ensuring strong measurement reliability is essential for supporting accurate data-driven decision-making. Thus, the purpose of this study was twofold: (i) to examine the reliability of countermovement vertical jump (CMJ) force-time metrics obtained using a portable force plate system (Hawkin Dynamics) and (ii) to determine whether absolute and relative reliability scores differ between well-trained individuals (i.e., athletes) and those less familiar with CMJ force-plate testing (i.e., non-athletes). Seventy-four participants volunteered to take part in this investigation, of whom thirty-nine were NCAA Division-I baseball and track-and-field athletes and thirty-five age-matched …


Creatine Supplementation Is Safe, Beneficial Throughout The Lifespan, And Should Not Be Restricted, Richard Kreider, Andrew Jagim, Jose Antonio, Douglas Kalman, Chad Kerksick, Jeffrey R. Stout, Robert Wildman, Rick Collins, Diego A. Bonilla Apr 2025

Creatine Supplementation Is Safe, Beneficial Throughout The Lifespan, And Should Not Be Restricted, Richard Kreider, Andrew Jagim, Jose Antonio, Douglas Kalman, Chad Kerksick, Jeffrey R. Stout, Robert Wildman, Rick Collins, Diego A. Bonilla

Faculty Scholarship

As researchers investigating creatine supplementation, we have become increasingly concerned about reports that government agencies are attempting to restrict the sale of dietary supplements, including dietary supplements containing creatine, to children and adolescents. Creatine is a naturally occurring compound found in every cell in the human body that plays a critical role in cellular metabolism. The daily turnover of creatine is about 2–4 grams/day, depending on muscle mass and physical activity levels (1, 2). About half of the daily need for creatine is synthesized in the body from amino acids (arginine, glycine, methionine) and stored as free creatine or phosphocreatine …


International Society Of Sports Nutrition Position Stand: Nutrition And Weight Cut Strategies For Mixed Martial Arts And Other Combat Sports, Anthony A. Ricci, Cassandra Evans, Charles Stull, Corey A. Peacock, Duncan N. French, Jeffrey R. Stout, David H. Fukuda, Paul La Bounty, Douglas Kalman, Andrew J. Galpin, Jaime Tartar, Sarah Johnson, Richard B. Kreider, Chad Kerksick, Bill I. Campbell, Aaron Jeffery, Chris Algieri, Jose Antonio Feb 2025

International Society Of Sports Nutrition Position Stand: Nutrition And Weight Cut Strategies For Mixed Martial Arts And Other Combat Sports, Anthony A. Ricci, Cassandra Evans, Charles Stull, Corey A. Peacock, Duncan N. French, Jeffrey R. Stout, David H. Fukuda, Paul La Bounty, Douglas Kalman, Andrew J. Galpin, Jaime Tartar, Sarah Johnson, Richard B. Kreider, Chad Kerksick, Bill I. Campbell, Aaron Jeffery, Chris Algieri, Jose Antonio

Faculty Scholarship

Following an extensive literature review, the International Society of Sports Nutrition (ISSN) has developed an official position on nutritional and weight cut strategies for combat sports. The type of combat sport, length of the fight camp, and time between weigh-in and competition are factors influencing nutritional and weight cut strategies. The following 16points constitute the Position Statement of the Society; the Research Committee has approved them. 1. Combat sports have differing weight categories, official weigh-in times, and competition frequencies, influencing the nutritional and weight cut strategies for training and competition. 2. As the duration of a combat match increases, >4 …


International Society Of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids, Ralf Jäger, Jeffrey L. Heilson, Sidney Abou Sawan, Broderick L. Dickerson, Megan Leonard, Richard B. Kreider, Chad M. Kerksick, Stephen M. Cornish, Darren G. Candow, Dean M. Cordingley, Scott C. Forbes, Grant M. Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I. Campbell, Shawn M. Arent, Jeffrey R. Stout, Douglas S. Kalman, Jose Antonio Jan 2025

International Society Of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids, Ralf Jäger, Jeffrey L. Heilson, Sidney Abou Sawan, Broderick L. Dickerson, Megan Leonard, Richard B. Kreider, Chad M. Kerksick, Stephen M. Cornish, Darren G. Candow, Dean M. Cordingley, Scott C. Forbes, Grant M. Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I. Campbell, Shawn M. Arent, Jeffrey R. Stout, Douglas S. Kalman, Jose Antonio

Faculty Scholarship

Position Statement: The International Society of Sports Nutrition (ISSN) presents this position based on a critical examination of the literature surrounding the effects of long-chain omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on exercise performance, recovery, and brain health. This position stand is intended to provide a scientific foundation for athletes, dietitians, trainers, and other practitioners regarding the effects of supplemental ω-3 PUFA in healthy and athletic populations. The following conclusions represent the official position of the ISSN:

  1. Athletes may be at a higher risk for ω-3 PUFA insufficiency.

  2. Diets rich in ω-3 PUFA, including supplements, are effective strategies …


Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance In Healthy Men, Chad M. Kerksick Dec 2024

Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance In Healthy Men, Chad M. Kerksick

Faculty Scholarship

Background: Choline is an essential nutrient required for proper cell functioning. Due to its status as a precursor to acetylcholine, an important neurotransmitter connected to cognition and neuromuscular function, maintaining or enhancing choline levels is of interest. Supplementation with alpha-glycerylphosphorycholine (A-GPC) can maintain choline levels, but its ability to offer support towards cognition remains an area of ongoing research. Methods: Using a randomized, double-blind, placebo-controlled, crossover approach, 20 resistance-trained males (31.3 ± 11.0 years, 178.6 ± 7.3 cm, 84.6 ± 11.4 kg, 15.4 ± 5.6% body fat) consumed either a placebo (PL), 630 mg A-GPC (HD), or 315 mg (LD) …


Effects Of Acacia Catechu And Scutellaria Baicalensis Extract On Cognitive Function In A Healthy Adult Population: A Double-Blind, Randomized, Placebo-Controlled Trial, Anthony M. Hagele, Petey Mumford, Diego De Gregorio, Connor J. Gaige, Ethan R. Hoffman, Kristen N. Gross, Kevin F. Holley, Leah E. Allen, Chad M. Kerksick Dec 2024

Effects Of Acacia Catechu And Scutellaria Baicalensis Extract On Cognitive Function In A Healthy Adult Population: A Double-Blind, Randomized, Placebo-Controlled Trial, Anthony M. Hagele, Petey Mumford, Diego De Gregorio, Connor J. Gaige, Ethan R. Hoffman, Kristen N. Gross, Kevin F. Holley, Leah E. Allen, Chad M. Kerksick

Faculty Scholarship

Flavonoids, known for their neuroprotective properties, are abundant in Acacia catechu and Scutellaria baicalensis. Yet, human studies on their combined effects are limited.

Objective

This study evaluated the cognitive effects of combined Acacia catechu and Scutellaria baicalensis supplementation in healthy adults.

Methods

In a randomized, double-blind, placebo-controlled trial, 26 males and 59 females (N = 85; 43 ± 8 yrs) consumed the test product (TP) containing 240 mg stem extract of Scutellaria baicalensis and 51 mg heartwood extract of Acacia catechu (UP326, Unigen, Tacoma, WA USA) or placebo (PLA) for four weeks. Cognitive function and biomarkers were assessed throughout …


International Society Of Sports Nutrition Position Stand: Β-Hydroxy-Β-Methylbutyrate (Hmb), John A. Rathmacher, Lisa M. Pitchford, Jeffrey R. Stout, Jeremy R. Townsend, Ralf Jägerg, Richard B. Kreider, Bill I. Campbell, Chad M. Kerksick, Patrick S. Harty, Darren G. Candow, Brandon M. Roberts, Shawn M. Arent, Douglas S. Kalman, Jose Antonio Dec 2024

International Society Of Sports Nutrition Position Stand: Β-Hydroxy-Β-Methylbutyrate (Hmb), John A. Rathmacher, Lisa M. Pitchford, Jeffrey R. Stout, Jeremy R. Townsend, Ralf Jägerg, Richard B. Kreider, Bill I. Campbell, Chad M. Kerksick, Patrick S. Harty, Darren G. Candow, Brandon M. Roberts, Shawn M. Arent, Douglas S. Kalman, Jose Antonio

Faculty Scholarship

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on an analysis of the literature regarding the effects of β-Hydroxy-β-Methylbutyrate (HMB). The following 12 points have been approved by the Research Committee of the Society: 1. HMB is a metabolite of the amino acid leucine that is naturally produced in both humans and other animals. Two forms of HMB have been studied: Calcium HMB (HMB-Ca) and a free acid form of HMB (HMB-FA). HMB-FA appears to lead to increased appearance of HMB in the bloodstream when compared to HMB-Ca, though recent results are mixed. 2. …


Dileucine Ingestion, But Not Leucine, Increases Lower Body Strength And Performance Following Resistance Training: A Double-Blind, Randomized, Placebo-Controlled Trial, Anthony M. Hagele, Joesi M. Krieger, Connor J. Gaige, Kevin F. Holley, Kristen N. Gross, Joshua M. Ianotti, Leah E. Allen, Paige J. Sutton, Logan S. Orr, Petey W. Mumford, Martin Pupura, Ralf Jager, Chad M. Kerksick Dec 2024

Dileucine Ingestion, But Not Leucine, Increases Lower Body Strength And Performance Following Resistance Training: A Double-Blind, Randomized, Placebo-Controlled Trial, Anthony M. Hagele, Joesi M. Krieger, Connor J. Gaige, Kevin F. Holley, Kristen N. Gross, Joshua M. Ianotti, Leah E. Allen, Paige J. Sutton, Logan S. Orr, Petey W. Mumford, Martin Pupura, Ralf Jager, Chad M. Kerksick

Faculty Scholarship

Background

The essential amino acid leucine (LEU) plays a crucial role in promoting resistance-training adaptations. Dileucine (DILEU), a LEU-LEU dipeptide, increases MPS rates, however its impact on resistance training outcomes remains unexplored. This study assessed the effects of DILEU supplementation on resistance training adaptations.

Methods

Using a randomized, double-blind, placebo-controlled approach, 34 resistance-trained males (age: 28.3 ± 5.9 years) consumed 2 grams of either DILEU monohydrate (RAMPS™, Ingenious Ingredients, L.P.), LEU, or placebo (PLA) while following a 4-day per week resistance training program for 10 weeks. Changes in body composition, 1-repetition maximum (1RM) and repetitions to failure (RTF) for leg …


Part Ii. Common Questions And Misconceptions About Creatine Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Ann F. Brown, Darren G. Candow, Philip D. Chilibeck, Stacey J. Ellery, Scott C. Forbes, Bruno Gualano, Andrew R. Jagim, Chad Kerksick, Richard B. Kreider, Sergej M. Ostojic, Eric S. Rawson, Michael D. Roberts, Hamilton Roschel, Abbie E. Smith-Ryan, Jeffrey R. Stout, Mark A. Tarnopolsky, Trisha A. Vandusseldorp, Darryn S. Willoughby, Tim N. Ziegenfuss Dec 2024

Part Ii. Common Questions And Misconceptions About Creatine Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Ann F. Brown, Darren G. Candow, Philip D. Chilibeck, Stacey J. Ellery, Scott C. Forbes, Bruno Gualano, Andrew R. Jagim, Chad Kerksick, Richard B. Kreider, Sergej M. Ostojic, Eric S. Rawson, Michael D. Roberts, Hamilton Roschel, Abbie E. Smith-Ryan, Jeffrey R. Stout, Mark A. Tarnopolsky, Trisha A. Vandusseldorp, Darryn S. Willoughby, Tim N. Ziegenfuss

Faculty Scholarship

Creatine monohydrate supplementation (CrM) is a safe and effective intervention for improving certain aspects of sport, exercise performance, and health across the lifespan. Despite its evidence-based pedigree, several questions and misconceptions about CrM remain. To initially address some of these concerns, our group published a narrative review in 2021 discussing the scientific evidence as to whether CrM leads to water retention and fat accumulation, is a steroid, causes hair loss, dehydration or muscle cramping, adversely affects renal and liver function, and if CrM is safe and/or effective for children, adolescents, biological females, and older adults. As a follow-up, the purpose …


Common Questions And Misconceptions About Energy Drinks: What Does The Scientific Evidence Really Show?, Jose Antonio, Brandi Antonio, Shawn M. Arent, Darren G. Candow, Guillermo Escalante, Cassandra Evans, Scott Forbes, David Fukuda, Maureen Gibbons, Patrick Harty, Andrew R. Jagim, Douglas S. Kalman, Chad Kerksick, Jennifer A. Kurtz, Joseph Lillis, Lonnie Lowery, Gianna F. Mastrofini, Scotty Mills, Michael Nelson, Flavia Pereira, Justin Roberts, Michael Sagner, Jeffrey Stout, Jaime Tartar, Adam Wells Dec 2024

Common Questions And Misconceptions About Energy Drinks: What Does The Scientific Evidence Really Show?, Jose Antonio, Brandi Antonio, Shawn M. Arent, Darren G. Candow, Guillermo Escalante, Cassandra Evans, Scott Forbes, David Fukuda, Maureen Gibbons, Patrick Harty, Andrew R. Jagim, Douglas S. Kalman, Chad Kerksick, Jennifer A. Kurtz, Joseph Lillis, Lonnie Lowery, Gianna F. Mastrofini, Scotty Mills, Michael Nelson, Flavia Pereira, Justin Roberts, Michael Sagner, Jeffrey Stout, Jaime Tartar, Adam Wells

Faculty Scholarship

Energy drinks are a commonly consumed beverage, and studies suggest a possible performance-enhancing effect. A Google Scholar search using the keywords “energy drinks” and “exercise” yields numerous results, underscoring the voluminous research on this topic. However, there are questions regarding the effectiveness and safety of energy drinks. These questions include, but are not limited to: (1) What are the main active ingredients in energy drinks? (2) Do energy drinks assist in weight management? (3) Do energy drinks enhance aerobic performance? (4) Do energy drinks enhance athletic speed? (5) Do energy drinks improve reaction time? (6) Do energy drinks enhance lean …


The Association Of Zero Walking Cadence Minutes With Sleep Quality In Adults 18 – 65, Trent A. Hargens, Matthew C. Scott, Meghan Peterson, Kimberly C. Bennett, Timothy Thome, Elizabeth S. Edwards Nov 2024

The Association Of Zero Walking Cadence Minutes With Sleep Quality In Adults 18 – 65, Trent A. Hargens, Matthew C. Scott, Meghan Peterson, Kimberly C. Bennett, Timothy Thome, Elizabeth S. Edwards

Faculty Scholarship

Purpose Physical activity (PA) guidelines suggest a link between PA, sedentary time, and sleep quality (SQ). Step cadence is an emerging proxy for PA intensity, with zero cadence (ZC) indicating sedentary time. No research has explored the relationship between ZC and SQ. This study examines the relationship between ZC and SC, compared to traditional PA and sedentary metrics, all measured via accelerometry. Methods Sleep and PA was assessed in 138 adults (53 male, 85 female, age = 23.5 ± 8.0 year.) via accelerometry. Sedentary, light, moderate, vigorous intensity PA, and ZC minutes per day were measured. SQ variables included sleep …


A Sex Comparison Of The Physical And Physiological Demands Of United States Marine Corps Recruit Training, Bridget A. Mcfadden, Harry P. Cintineo, Alexa J. Chandler, Gianna F, Mastrofini, Caroline Vicenty, Patrick Peterson, Mita Lovalekar, Bradley Nindl, Shawn M. Arent Oct 2024

A Sex Comparison Of The Physical And Physiological Demands Of United States Marine Corps Recruit Training, Bridget A. Mcfadden, Harry P. Cintineo, Alexa J. Chandler, Gianna F, Mastrofini, Caroline Vicenty, Patrick Peterson, Mita Lovalekar, Bradley Nindl, Shawn M. Arent

Faculty Scholarship

PURPOSE: to monitor USMC recruits throughout training to comparatively assess workload, sleep, stress, and performance responses in men and women.

METHODS: 278 recruits (M = 180 & W = 98; Age = 19 ± 2y) were monitored and tested. Workload, sleep, and stress assessments occurred at weeks 2, 7/8, and 11 of training. Workload (energy expenditure per kg body mass [EE], distance [DIS], steps) and sleep (continuity & duration) were tracked over 72-hour periods using wearable accelerometry and heart rate devices. Stress was determined through salivary cortisol. Performance testing (vertical jump [CMJ] and isometric mid-thigh pull [IMTP]), occurred …


Differences In Perceived Energy And Macronutrient Requirements Across Divisions In Ncaa Athletes, K. Michelle Singleton, Andrew Jagim, Jamie Mcallister-Deitrick, Marcos Daou, Chad M. Kerksick Jun 2024

Differences In Perceived Energy And Macronutrient Requirements Across Divisions In Ncaa Athletes, K. Michelle Singleton, Andrew Jagim, Jamie Mcallister-Deitrick, Marcos Daou, Chad M. Kerksick

Faculty Scholarship

Background

Sports nutrition is an impactful component to sports performance. The purpose of the current study was to investigate the sports nutrition knowledge of National Collegiate Athletic Association collegiate athletes and assess self-reported perceived requirements for energy and macronutrient intake. A secondary aim was to evaluate the awareness of physical and emotional perceptions associated with mindful eating.

Methods

Participants included NCAA Division I (DI, n = 45), II (DII, n = 31), and III (DIII, n = 47) athletes. Athletes completed a validated questionnaire designed to assess sports nutrition knowledge and were asked questions about their perceived dietary energy and …


The Effects Of A Brand-Specific, Hemp-Derived Cannabidiol Product On Physiological, Biochemical, And Psychometric Outcomes In Healthy Adults: A Double-Blind, Randomized Clinical Trial, Gianna F. Mastrofini, Bridget A. Mcfadden, Alexa J. Chandler, Blaine S. Lints, Harry P. Cintineo, Nathaniel D. Rhoades, Caroline S. Vincenty, Sten O. Stray-Gundersen, Abbi D. Lane, Shawn M. Arent Jun 2024

The Effects Of A Brand-Specific, Hemp-Derived Cannabidiol Product On Physiological, Biochemical, And Psychometric Outcomes In Healthy Adults: A Double-Blind, Randomized Clinical Trial, Gianna F. Mastrofini, Bridget A. Mcfadden, Alexa J. Chandler, Blaine S. Lints, Harry P. Cintineo, Nathaniel D. Rhoades, Caroline S. Vincenty, Sten O. Stray-Gundersen, Abbi D. Lane, Shawn M. Arent

Faculty Scholarship

Background

Cannabidiol (CBD) is a non-psychoactive phyto-cannabinoid derived from the Cannabis sativa plant. CBD exhibits various interactions at receptor sites, prompting the research of its potential anti-inflammatory, immunomodulatory, psychological, and pain-relieving effects. This study aimed to investigate the physiological, biochemical, and psychometric effects of a brand-specific, hemp-derived CBD product in healthy adults over a 12-week observation period.

Methods

54 healthy males and females (age = 25 ± 7y; BMI = 24.82 ± 3.25 kg/m2) recruited from a large Southeastern University completed the study. Participants arrived at the laboratory after > 8 h of fasting, and > 48 h without alcohol consumption and …


International Society Of Sports Nutrition Position Stand: Ketogenic Diets, Alex Leaf, Jeffrey A. Rothschild, Tim M. Sharpe, Stacy T. Sims, Chad J. Macias, Geoff G. Futch, Michael D. Roberts, Jeffrey R. Stout, Michael J. Ormsbee, Alan A. Aragon, Bill I. Campbell, Shawn M. Arent, Dominic P. D'Agostino, Michelle T. Barrack, Chad Kerksick, Richard B. Kreider, Douglas S. Kalman, Jose Antonio Jun 2024

International Society Of Sports Nutrition Position Stand: Ketogenic Diets, Alex Leaf, Jeffrey A. Rothschild, Tim M. Sharpe, Stacy T. Sims, Chad J. Macias, Geoff G. Futch, Michael D. Roberts, Jeffrey R. Stout, Michael J. Ormsbee, Alan A. Aragon, Bill I. Campbell, Shawn M. Arent, Dominic P. D'Agostino, Michelle T. Barrack, Chad Kerksick, Richard B. Kreider, Douglas S. Kalman, Jose Antonio

Faculty Scholarship

Position statement

The International Society of Sports Nutrition (ISSN) provides an objective and critical review of the use of a ketogenic diet in healthy exercising adults, with a focus on exercise performance and body composition. However, this review does not address the use of exogenous ketone supplements. The following points summarize the position of the ISSN:

1. A ketogenic diet induces a state of nutritional ketosis, which is generally defined as serum ketone levels above 0.5 mM. While many factors can impact what amount of daily carbohydrate intake will result in these levels, a broad guideline is a daily dietary …


A Dose-Response Study To Examine Paraxanthine's Impact On Energy Expenditure, Hunger, Appetite, And Lipolysis, Kristen N. Gross, Leah E. Allen, Anthony M. Hagele, Joesi M. Krieger, Paige J. Sutton, Esther Duncan, Petey W. Mumford, Ralf Jäger, Martin Purpura, Chad M. Kerksick May 2024

A Dose-Response Study To Examine Paraxanthine's Impact On Energy Expenditure, Hunger, Appetite, And Lipolysis, Kristen N. Gross, Leah E. Allen, Anthony M. Hagele, Joesi M. Krieger, Paige J. Sutton, Esther Duncan, Petey W. Mumford, Ralf Jäger, Martin Purpura, Chad M. Kerksick

Faculty Scholarship

This study investigated if paraxanthine (PX) impacts energy expenditure, lipolysis and perceptual responses. In a randomized, double-blind, placebo-controlled, crossover fashion, 21 adults (13 M, 8 F; 26.0 ± 6.4 years, 174.9 ± 11.5 cm, 81.0 ± 15.7 kg body mass, 26.3 ± 3.4 kg/m2) consumed a placebo (PLA), 100 mg (PX100), 200 mg (PX200), and 300 mg of PX (PX300, enfinity®, Ingenious Ingredients, L.P. Lewisville, TX, USA). Venous blood was collected 0, 30, 60, 90, 120 and 180 min (min) after ingestion and analyzed for glycerol and free fatty acids. Resting hemodynamics, metabolic rate and perceptual indicators of hunger, appetite …


Common Questions And Misconceptions About Protein Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Cassandra Evans, Arny A. Ferrando, Jeffrey R. Stout, Brandi Antonio, Harry P. Cintineo, Patrick Harty, Shwn M. Arent, Darren G. Candow, Scott C. Forbes, Chad M. Kerksick, Flavia Pereira, Drew Gonzalez, Richard B. Kreider Apr 2024

Common Questions And Misconceptions About Protein Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Cassandra Evans, Arny A. Ferrando, Jeffrey R. Stout, Brandi Antonio, Harry P. Cintineo, Patrick Harty, Shwn M. Arent, Darren G. Candow, Scott C. Forbes, Chad M. Kerksick, Flavia Pereira, Drew Gonzalez, Richard B. Kreider

Faculty Scholarship

Protein supplementation often refers to increasing the intake of this particular macronutrient through dietary supplements in the form of powders, ready-to-drink shakes, and bars. The primary purpose of protein supplementation is to augment dietary protein intake, aiding individuals in meeting their protein requirements, especially when it may be challenging to do so through regular food (i.e. chicken, beef, fish, pork, etc.) sources alone. A large body of evidence shows that protein has an important role in exercising and sedentary individuals. A PubMed search of “protein and exercise performance” reveals thousands of publications. Despite the considerable volume of evidence, it is …


Peripheral Quantitative Computed Tomography Is A Valid Imaging Technique For Tracking Changes In Skeletal Muscle Cross-Sectional Area, Bradley A. Ruple, Christopher G. Vann, Casey L. Sexton, Shelby C. Osburn, Morgan A. Smith, Joshua S. Godwin, Petey W. Mumford, Matt S. Stock, Michael D. Roberts, Kaelin C. Young Apr 2024

Peripheral Quantitative Computed Tomography Is A Valid Imaging Technique For Tracking Changes In Skeletal Muscle Cross-Sectional Area, Bradley A. Ruple, Christopher G. Vann, Casey L. Sexton, Shelby C. Osburn, Morgan A. Smith, Joshua S. Godwin, Petey W. Mumford, Matt S. Stock, Michael D. Roberts, Kaelin C. Young

Faculty Scholarship

Peripheral quantitative computed tomography (pQCT) has recently expanded to quantifying skeletal muscle, however its validity to determine muscle cross‐sectional area (mCSA) compared to magnetic resonance imaging (MRI) is unknown. Eleven male participants (age: 22 ± 3 y) underwent pQCT and MRI dual‐leg mid‐thigh imaging before (PRE) and after (POST) 6 weeks of resistance training for quantification of mid‐thigh mCSA and change in mCSA. mCSA agreement at both time points and absolute change in mCSA across time was assessed using Bland‐ Altman plots for mean bias and 95% limits of agreement (LOA), as well as Lin's concordance correlation coefficients (CCC). Both …


It’S Dead! Can Postbiotics Really Help Performance And Recovery? A Systematic Review, Chad M. Kerksick, Jessica M. Moon, Ralf Jäger Mar 2024

It’S Dead! Can Postbiotics Really Help Performance And Recovery? A Systematic Review, Chad M. Kerksick, Jessica M. Moon, Ralf Jäger

Faculty Scholarship

In recent years, postbiotics have increased in popularity, but the potential relevancy of postbiotics for augmenting exercise performance, recovery, and health is underexplored. A systematic literature search of Google Scholar and PubMed databases was performed with the main objective being to identify and summarize the current body of scientific literature on postbiotic supplementation and outcomes related to exercise performance and recovery. Inclusion criteria for this systematic review consisted of peer-reviewed, randomized, double-blind, and placebo-controlled trials, with a population including healthy men or women >18 years of age. Studies required the incorporation of a postbiotic supplementation regimen and an outcome linked …


Milk Or Kefir, In Comparison To Water, Do Not Enhance Running Time-Trial Performance In Endurance Master Athletes, Kristen N. Gross, Patrick S. Harty, Joesi M. Krieger, Petey W. Mumford, Kyle L. Sunderland, Anthony M. Hagele, Chad Kerksick Mar 2024

Milk Or Kefir, In Comparison To Water, Do Not Enhance Running Time-Trial Performance In Endurance Master Athletes, Kristen N. Gross, Patrick S. Harty, Joesi M. Krieger, Petey W. Mumford, Kyle L. Sunderland, Anthony M. Hagele, Chad Kerksick

Faculty Scholarship

This study compared flavored kefir (KFR) and flavored milk (MLK) as a recovery drink in endurance master athletes. Using a randomized, placebo-controlled, non-blinded crossover design, 11 males and females completed three testing visits whilst acutely ingesting either KFR, MLK, or water as a placebo (PLA). KFR supplementation occurred for 14 days before the KFR-testing day, followed by a 3-week washout period. Testing visits consisted of an exhausting-exercise (EE) bout, a 4-h rest period where additional carbohydrate feeding was provided, and a treadmill 5 km time trial (TT). The Gastrointestinal Symptom Rating Scale (GSRS) survey was assessed at four timepoints. Blood …


Multi-Strain Probiotic Improves Subjective Sleep Quality With No Impact On Body Composition, Hemodynamics, And Physical Activity, Chad Kerksick, Jessca Moon, Kylie Walden, Anthony Hagele, L. E. Allen, Connor J. Gaige, Joesi M. Krieger, Ralf Jäger, Marco Pane, Petey Mumford Jan 2024

Multi-Strain Probiotic Improves Subjective Sleep Quality With No Impact On Body Composition, Hemodynamics, And Physical Activity, Chad Kerksick, Jessca Moon, Kylie Walden, Anthony Hagele, L. E. Allen, Connor J. Gaige, Joesi M. Krieger, Ralf Jäger, Marco Pane, Petey Mumford

Faculty Scholarship

The objective of the study was to examine the impact of a multi-strain probiotic (MSP) on sleep, physical activity, and body composition changes. We used a randomised, double-blind, placebo-controlled approach with 70 healthy men and women (31.0 ± 9.5 years, 173.0 ± 10.4 cm, 73.9 ± 13.8 kg, 24.6 ± 3.5 kg/m2) supplemented daily with MSP (4 × 109 live cells Limosilactobacillus fermentum LF16, Lacticaseibacillus rhamnosus LR06, Lactiplantibacillus plantarum LP01, and Bifidobacterium longum 04; Probiotical S.p.A., Novara, Italy) or placebo (PLA). In response to supplementation (after 0, 2, 4, and 6 weeks of supplementation) and 3 weeks after stopping supplementation, …


Changes In Energy Expenditure, Dietary Intake, And Energy Availability Across An Entire Collegiate Women’S Basketball Season: Erratum, Breyannah R. Zanders, Brad S. Currier, Patrick Harty, Hannah A. Zabriskie, Charles R. Smith, Richard A. Stecker, Scott R. Richmond, Andrew R. Jagim, Chad Kerksick Dec 2023

Changes In Energy Expenditure, Dietary Intake, And Energy Availability Across An Entire Collegiate Women’S Basketball Season: Erratum, Breyannah R. Zanders, Brad S. Currier, Patrick Harty, Hannah A. Zabriskie, Charles R. Smith, Richard A. Stecker, Scott R. Richmond, Andrew R. Jagim, Chad Kerksick

Faculty Scholarship

Erratum


The Effects Of Protein And Carbohydrate Supplementation, With And Without Creatine, On Occupational Performance In Firefighters, Kaia Elstad, Conley Malone, Joel Luedke, Salvadore J. Jaime, Ward C. Dobbs, Thomas Almonroeder, Chad M. Kerksick, Adam Markert, Andrew R. Jagim Dec 2023

The Effects Of Protein And Carbohydrate Supplementation, With And Without Creatine, On Occupational Performance In Firefighters, Kaia Elstad, Conley Malone, Joel Luedke, Salvadore J. Jaime, Ward C. Dobbs, Thomas Almonroeder, Chad M. Kerksick, Adam Markert, Andrew R. Jagim

Faculty Scholarship

Background: The purpose of this study was to assess the effects of protein and carbohydrate supplementation, with and without creatine, on occupational performance in firefighters. Methods: Using a randomized, double-blind approach, thirty male firefighters (age: 34.4 ± 8.4 yrs., height: 1.82 ± 0.07 m; weight: 88.6 ± 12.5 kg; BF%: 17.2 ± 5.8%) were randomized to receive either (A.) 25 g of whey protein isolate + 25 g of carbohydrate powder (ProCarb group); or (B.) ProCarb + 5 g of creatine (Creatine group) in a double-blind fashion over a period of 21–26 days (depending on shift rotations) to evaluate …


Naturally Bicarbonated Water Supplementation Does Not Improve Anaerobic Cycling Performance Or Blood Gas Parameters In Active Men And Women, Anthony M. Hagele, Johnathan L. Boring, Jessica M. Moon, Kyle L. Sunderland, Petey W. Mumford, Chad M. Kerksick Dec 2023

Naturally Bicarbonated Water Supplementation Does Not Improve Anaerobic Cycling Performance Or Blood Gas Parameters In Active Men And Women, Anthony M. Hagele, Johnathan L. Boring, Jessica M. Moon, Kyle L. Sunderland, Petey W. Mumford, Chad M. Kerksick

Faculty Scholarship

The completion of high-intensity exercise results in robust perturbations to physiologic homeostasis, challenging the body’s natural buffering systems to mitigate the accumulation of metabolic by-products. Supplementation with bicarbonate has previously been used to offset metabolic acidosis, leading to improvements in anaerobic exercise performance. Purpose: The purpose of this study was to investigate the presence of ergogenic properties in naturally occurring low-dose bicarbonated water and their effects on anaerobic cycling performance and blood gas kinetics in recreationally active men and women. Methods: Thirty-nine healthy, recreationally active men and women (28.1 ± 8.0 years, 169.8 ± 11.7 cm, 68.9 ± 10.8 kg, …


Impact Of Probiotic Veillonella Atypica Fb0054 Supplementation On Anaerobic Capacity And Lactate, Kristen Gross, Marina Santiago, Joesi M. Krieger, Anthony M. Hagele, Kinga Zielinska, Jonathan Scheiman, Ralf Jäger, Alex Kostic, Chad Kerksick Dec 2023

Impact Of Probiotic Veillonella Atypica Fb0054 Supplementation On Anaerobic Capacity And Lactate, Kristen Gross, Marina Santiago, Joesi M. Krieger, Anthony M. Hagele, Kinga Zielinska, Jonathan Scheiman, Ralf Jäger, Alex Kostic, Chad Kerksick

Faculty Scholarship

Seven healthy, physically active men (n = 3) and women (n = 4) (30.7 ± 7.5 years, 172.7 ± 8.7 cm, 70.4 ± 11.6 kg, 23.6 ± 4.1 kg/m², 49.2 ± 8.4 mL/kg/min) supplemented for 14 days with a placebo (PLA) or 1 × 10¹⁰ CFU doses of the probiotic Veillonella atypica FB0054 (FitBiomics, New York, NY). Participants had safety panels, hemodynamics, lactate, and anaerobic capacity assessed. Stool samples were collected to evaluate for metagenomic and metabolomic changes. Exhaustion times were not different between groups, whereas anaerobic capacity tended to shorten with PLA (61.14 ± 72.04 s; 95% CI: −5.49, …


International Society Of Sports Nutrition Position Stand: Effects Of Essential Amino Acid Supplementation On Exercise And Performance, Arny A. Ferrnado, Robert R. Wolfe, Katie R. Hirsch, David D. Church, Shiloah A. Kviatkovsky, Michael D. Roberts, Jeffrey R. Stout, Drew E. Gonzalez, Ryan J. Sowinski, Richard B. Kreider, Chad Kerksick, Nicholas A. Burd, Stefan M. Pasiakos, Michael J. Ormsbee, Shawn M. Arent, Paul J. Arciero, Bill I. Campbell, Trisha A. Van Dusseldorp, Ralf Jager, Darryn S. Willoughby, Douglas S. Kalman, Jose Antonio Oct 2023

International Society Of Sports Nutrition Position Stand: Effects Of Essential Amino Acid Supplementation On Exercise And Performance, Arny A. Ferrnado, Robert R. Wolfe, Katie R. Hirsch, David D. Church, Shiloah A. Kviatkovsky, Michael D. Roberts, Jeffrey R. Stout, Drew E. Gonzalez, Ryan J. Sowinski, Richard B. Kreider, Chad Kerksick, Nicholas A. Burd, Stefan M. Pasiakos, Michael J. Ormsbee, Shawn M. Arent, Paul J. Arciero, Bill I. Campbell, Trisha A. Van Dusseldorp, Ralf Jager, Darryn S. Willoughby, Douglas S. Kalman, Jose Antonio

Faculty Scholarship

Position Statement: The International Society of Sports Nutrition (ISSN) presents this position based on a critical examination of literature surrounding the effects of essential amino acid (EAA) supplementation on skeletal muscle maintenance and performance. This position stand is intended to provide a scientific foundation to athletes, dietitians, trainers, and other practitioners as to the benefits of supplemental EAA in both healthy and resistant (aging/clinical) populations. EAAs are crucial components of protein intake in humans, as the body cannot synthesize them. The daily recommended intake (DRI) for protein was established to prevent deficiencies due to inadequate EAA consumption. The following conclusions …


Prevalence Of Adulteration In Dietary Supplements And Recommendations For Safe Supplement Practices In Sport, Andrew R. Jagim, Patrick Harty, Jacob L. Erickson, Grant M. Tinsley, Dan Garner, Andrew J. Galpin Sep 2023

Prevalence Of Adulteration In Dietary Supplements And Recommendations For Safe Supplement Practices In Sport, Andrew R. Jagim, Patrick Harty, Jacob L. Erickson, Grant M. Tinsley, Dan Garner, Andrew J. Galpin

Faculty Scholarship

The prevalence of dietary supplement use among athletes continues to rise with 60–80% of athletes often reporting current or previous use of dietary supplements. While select dietary ingredients have been shown to improve acute performance and enhance training adaptations over time, it is important to still consider the risk vs. reward for athletes before opting to consume a dietary supplement. Previous work has indicated that certain dietary supplements may pose risks for inadvertent doping, may be susceptible to mislabelling, could be banned by certain governing bodies of sport, or pose health risks for certain populations. The purpose of the current …