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The Association Of Exercise Training Modalities With Circulating Branched Chain Amino Acid And Ketone Body Levels In Patients With Type 2 Diabetes, Ryan Andrew Flynn
The Association Of Exercise Training Modalities With Circulating Branched Chain Amino Acid And Ketone Body Levels In Patients With Type 2 Diabetes, Ryan Andrew Flynn
Theses and Dissertations
Background: Elevated levels of circulating branched-chain amino acids (BCAA) and ketone bodies are recognized as biomarkers for cardiovascular disease (CVD) and other pathological conditions in type-2 diabetes mellitus (T2DM). Aerobic exercise interventions have been shown to decrease the levels of these markers, suggesting improved metabolic status and reduced risk of CVD. However, the efficacy of resistance training and concurrent programs in reducing BCAA and ketone body levels has not been well researched.
Methods: The current study was performed as a secondary analysis of the HART-D trial, a 9-month randomized, controlled exercise-training trial of 262 participants with T2DM. Participants were randomized …