Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Kinesiology
The Role Of Nitric Oxide, Acetylcholine, And Vasoactive Intestinal Peptide On Skin Blood Flow During In-Vivo Electrical Field Stimulation, Robert S. Thiebaud
The Role Of Nitric Oxide, Acetylcholine, And Vasoactive Intestinal Peptide On Skin Blood Flow During In-Vivo Electrical Field Stimulation, Robert S. Thiebaud
Theses and Dissertations
The purpose of this study was to characterize a novel technique to study neurogenic control of cutaneous vasodilation. We monitored skin blood flow (SkBF) during in-vivo electrical stimulation (e-stim) intended to activate cutaneous nerves and used intradermal microdialysis to deliver receptor antagonists to characterize their contribution to cutaneous vasodilation. We examined the role of acetylcholine receptors (RACh), nitric oxide (NO), and vasoactive intestinal peptide receptors (RVIP) on the cutaneous vasodilation induced by e-stim in the absence of the sympathetic adrenergic nervous system. Six men and three women participated in the study. Three intradermal microdialysis probes were placed in the skin …
The Effects Of Low Frequency Ultrasound In Transdermal Drug Delivery, Aaron M. Wells
The Effects Of Low Frequency Ultrasound In Transdermal Drug Delivery, Aaron M. Wells
Theses and Dissertations
Objective: Determine if varying ultrasound frequency affects the delivery of 10% hydrocortisone concentrations during phonophoresis. Utilize intramuscular microdialysis probe for drug collection, thus improving the experimental model. Methods: Thirty one (10 in groups 1 and 2, 11 in group 3) healthy subjects participated in this study. Interventions: Subjects were randomly assigned to one of three treatment groups receiving 10 minute ultrasound treatments applied to a standardized area of the gastrocnemius muscle of the right leg. The ultrasound was performed over the treated area using a 10% hydrocortisone compound mixed with standard ultrasound gel. The contralateral limb served as the control …