Kinesiology Commons^™

The Influence Of Habitual Physical Activity And Sedentary Behavior On Objective And Subjective Hot Flashes At Midlife, Sarah Witkowski, Quinn White, Sofiya Shreyer, Daniel E. Brown, Lynette Leidy Sievert

Exercise and Sport Studies: Faculty Publications

The years surrounding the transition to menopause are marked by multiple challenges to health. Hot flashes are a commonly reported symptom of women at this time and their frequency has been associated with disease risk. Regular physical activity and reduced sedentary time are recommended for health and wellbeing. However, the effect of physical activity and sedentary behavior on hot flashes remains unclear. OBJECTIVE: The purpose of this study was to evaluate relationships between physical activity, sedentary time and hot flashes during both waking and sleeping periods using concurrent objective and subjective measures of hot flashes in midlife women. METHODS: Women …

Acute Increases In Physical Activity And Temperature Are Associated With Hot Flash Experience In Midlife Women, Sarah Witkowski, Quinn White, Sofiya Shreyer, Randi L. Garcia, Daniel E. Brown, Lynnette Leidy Sievert

Exercise and Sport Studies: Faculty Publications

Objective: This study determined the association between acute changes in physical activity, temperature and humidity and 24-hour subjective and objective hot flash experience.

Methods: Data collection occurred during the cooler months of the year in Western Massachusetts (October-April). Women aged 45-55 across 3 menopause stages (n=270) were instrumented with ambulatory monitors to continuously measure hot flashes, physical activity, temperature and humidity for 24-hours. Objective hot flashes were assessed via sternal skin conductance, and subjective hot flashes were recorded by pressing an event marker and data logging. Physical activity was measured with wrist-worn accelerometers and used to define sleep and wake …

Physical Activity And Exercise For Hot Flashes: Trigger Or Treatment?, Sarah Witkowski, Rose Evard, Jacquelyn J. Rickson, Quinn White, Lynnette Leidy Sievert

Exercise and Sport Studies: Faculty Publications

Importance and Objective: Hot flashes (HFs) are a prevalent feature of menopause. Hot flashes can be bothersome and affect quality of life. However, HFs have also been associated with the risk for cardiovascular disease. Therefore, providing current evidence on the effect of therapies to reduce HFs can help patients and providers with decision making. This review provides details on the scientific evidence to date related to the effect of physical activity (PA) and exercise to alter the HF experience in women

Methods: The PubMed database was searched between June 2020 and June 2022 for currently available evidence regarding the relation …

A Comparison Of Stress, Symptoms, Physical Activity, And Adiposity Among Women At Midlife Before And During The Pandemic, Lynnette Leldy Stevert, Sofiya Shreyer, Ashley Boudreau, Sarah Witkowski, Daniel E. Brown

Exercise and Sport Studies: Faculty Publications

Background: The COVID-19 pandemic presented challenges that disproportionately impacted women. Household roles typically performed by women (such as resource acquisition and caretaking) became more difficult due to financial strain, fear of infection, and limited childcare options among other concerns. This research draws from an ongoing study of hot flashes and brown adipose tissue to examine the health-related effects of the COVID-19 pandemic among 162 women aged 45–55 living in western Massachusetts.

Methods: We compared women who participated in the study pre- and early pandemic with women who participated mid-pandemic and later-pandemic (when vaccines became widely available). We collected self-reported symptom …

Endurance Exercise Training Effects On Body Fatness, Vo2max Hdl-C Subfractions, And Glucose Tolerance Are Influenced By A Plin Haplotype In Older Caucasians, Nathan T. Jenkins, Jennifer A. Mckenzie, Coleen M. Damcott, Sarah Witkowski, James M. Hagberg

Exercise and Sport Studies: Faculty Publications

Perilipins are lipid droplet-coating proteins that regulate intracellular lipolysis in adipocytes. A haplotype of two perilipin gene (PLIN) single nucleotide polymorphisms, 13041A>G and 14995A>>T, has been previously associated with obesity risk. Furthermore, the available data indicate that this association may be modified by sex. We hypothesized that this haplotype would associate with body fatness, aerobic fitness, and a number of cardiovascular (CV) risk factor phenotypes before and after a 6-mo endurance exercise training program in sedentary older Caucasians. The major haplotype group (13041A/14995A; n = 57) had significantly lower body mass index (BMI) and body fatness compared with …

Effects Of Acute And Chronic Endurance Exercise On Intracellular Nitric Oxide In Putative Endothelial Progenitor Cells: Role Of Napdh Oxidase, Nathan T. Jenkins, Sarah Witkowski, Espen E. Spangenburg, James M. Hagberg

Exercise and Sport Studies: Faculty Publications

We sought to delineate the effects of acute and chronic exercise on the regulation of intracellular nitric oxide (NOi) production in putative endothelial progenitor cells (EPCs). Putative EPC colony-forming units (CFUEC) were cultured from blood drawn before and after 30 min of treadmill exercise at 75% of maximal oxygen uptake in active (n = 8) and inactive (n = 8) men. CFU-EC were similar between groups at baseline, but increased after exercise in active men only (P = 0.04). CFU-EC expressed lower NADPH oxidase subunit gp91 phox mRNA and elevated endothelial nitric oxide synthase mRNA in active relative to inactive …