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Kinesiology Commons

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Full-Text Articles in Kinesiology

Examining The Effects Of Interleukin-6 On Appetite Regulatory Peptides In Lean And Obese Sedentary Males, Greg L. Mckie Jan 2018

Examining The Effects Of Interleukin-6 On Appetite Regulatory Peptides In Lean And Obese Sedentary Males, Greg L. Mckie

Theses and Dissertations (Comprehensive)

Acute moderate-intensity exercise transiently suppresses appetite via fluctuations in the appetite-regulatory peptides acylated ghrelin (AG), peptide tyrosine-tyrosine3-36 (PYY3-36), and active glucagon-like peptide-1 (GLP-1). Importantly, these effects do not lead to compensatory changes in energy intake in normal weight or obese individuals, highlighting the potential for exercise to induce acute energy deficits. One potential mechanism for these effects is increased post-exercise plasma concentrations of interleukin (IL)-6, as IL-6 has demonstrated appetite-inhibitory effects in animal and cell culture models. Given obesity is characterized by a state of chronic low-grade inflammation and associated with upregulated IL-6, this study sought to …


Estimates Of Persistent Inward Current In Human Motor Neurons During Postural Sway, Ryan Foley, Jayne M. Kalmar Dr. Jan 2015

Estimates Of Persistent Inward Current In Human Motor Neurons During Postural Sway, Ryan Foley, Jayne M. Kalmar Dr.

Theses and Dissertations (Comprehensive)

Persistent inward current (PIC) is a membrane property critical for increasing gain of motor neuron output. In humans, most estimates of PIC are made from plantarflexor or dorsiflexor motor units with the participant in a seated position with the knee flexed. This seated and static posture neglects the task-dependent nature of the monoaminergic drive that modulates PIC activation. Seated estimates may drastically underestimate the amount of PIC that occurs in human motor neurons during functional movement. The current study estimated PIC using the conventional paired motor unit technique which uses the difference between reference unit firing frequency at test unit …