Immunology and Infectious Disease Commons^™

Structure-Property Relationships At The Nano-Bio Interface: Engineering The Nanoparticle Surface For Immunomodulation, Daniel Fernando Moyano Marino

Doctoral Dissertations

Each year, a variety of novel nanomaterials are being developed with the objective of treating different diseases. However, since nanomaterials are foreign to the human body, one of the principal factors that limit their use is the encounter with the first line of defense from the body: the immune system. If this interaction is not taken into account, an undesired recognition takes place and the efficiency of nanoparticle based therapies is dramatically reduced. As such, understanding the rules that govern this recognition is of prime importance in the field of nanomedicine. Following this line of thoughts (the driving force), the …