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Immunology and Infectious Disease Commons™
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Full-Text Articles in Immunology and Infectious Disease
Mycobacterium Marinum Infection After Exposure To Coal Mine Water, Moises A. Huaman, Julie A. Ribes, Kristine M. Lohr, Martin E. Evans
Mycobacterium Marinum Infection After Exposure To Coal Mine Water, Moises A. Huaman, Julie A. Ribes, Kristine M. Lohr, Martin E. Evans
Internal Medicine Faculty Publications
Mycobacterium marinum infection has been historically associated with exposure to aquariums, swimming pools, fish, or other marine fauna. We present a case of M marinum left wrist tenosynovitis and elbow bursitis associated with a puncture injury and exposure to coal mine water in Illinois.
The Role Of Batf2 In Lps/Ifnγ Polarized Macrophages, Marie A. Gehman
The Role Of Batf2 In Lps/Ifnγ Polarized Macrophages, Marie A. Gehman
Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics
Transcription factors regulate distinct macrophage functions by regulating gene expression in response to micro-environmental cues. This functional plasticity is critical for regulating innate and adaptive immune responses during infection and during chronic disease processes including inflammatory diseases and cancer. Microarray analysis of macrophages polarized to a pro-inflammatory (M1) phenotype with LPS and IFNγ revealed that basic leucine zipper transcription factor ATF-like 2 (Batf2), a member of the AP1 transcription factors, is selectively upregulated in M1 macrophages compared to anti-inflammatory IL-4-polarized (M2) macrophages. The initial hypothesis was that Batf2 is a master regulator of gene expression that orchestrates M1 polarization. To …