Immunology and Infectious Disease Commons^™

Generation Of Chimeric Rhinoviruses Presenting Sars-Cov-2 Broadly Neutralizing Epitopes And Their Antigenicity Characterization, Danish Ansari

Biotechnology Theses

The global COVID pandemic is not yet fully under control as there were over 21 million new cases of SARS-CoV-2 infections and over 50,000 deaths globally as of January of 2022. A heavily mutated variant of concern, Omicron is responsible for most of these cases which demands an urgency for a new vaccine. NIH reports over 180 vaccine candidates that use various strategies currently in development. However, a recurring concern with these vaccines is that the continuous viral mutations decrease the efficacy of vaccines. Therefore, we proposed to construct a human rhinovirus (HRV) based chimeric virus containing highly conserved, broadly …

Spike Protein Structural Dynamics Of Sars-Cov-2 Coronaviruses Studied Using Molecular Dynamics, William Strickland

Biological Sciences Undergraduate Honors Theses

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has overwhelmingly impacted the global population, accounting for millions of confirmed infections and deaths over the last year. The virus’s influence on the health and safety of individuals, the economy, and daily life has been disruptive and devastating. While SARS-CoV-2 and SARS-CoV-1, two closely related members of the SARS coronaviruses, have shown the ability to cross the species barrier and infect humans, SARS-CoV-2 has predominantly been the virus responsible for the number of infections presently known. SARS-CoV-2 has also proven to be volatile, as many variants have …

Full Issue: The International Undergraduate Journal Of Health Sciences, Volume 1, Issue 1, June 2021

International Undergraduate Journal of Health Sciences

The full June 2021 issue (Volume 1, Issue 1) of the International Undergraduate Journal of Health Sciences

Media Analysis Of Coverage Of Environmental Issues In The Midst Of A Pandemic, Alexandria N. Miller, Lucia A. Bolles

Thinking Matters Symposium

This research aimed to answer the question “has the coronavirus impacted the print media’s coverage of important environmental issues?” The research analyzed 2 different print newspapers - The New York Times and the Wall Street Journal - to determine if there was a change in coverage of environmental news as the coronavirus spread in the US. Data for stories published in the first four days of every month from March through September was compiled for 2019 and 2020. Our findings showed a 78.85% decrease in coverage of environmental issues between 2019 and 2020 when stories related to the coronavirus pandemic …

Piglet Immunization With A Spike Subunit Vaccine Enhances Disease By Porcine Epidemic Diarrhea Virus, Jieshi Yu, Chithra Sreenivasan, Tirth Uprety, Rongyuan Gao, Chen Huang, Ella J. Lee, Steven Lawson, Julie Nelson, Jane Christopher-Hennings, Radhey S. Kaushik, Eric Nelson, Diego G. Diel, Ben M. Hause, Feng Li, Dan Wang

Maxwell H. Gluck Equine Research Center Faculty Publications

Immunization with an insect cell lysate/baculovirus mixture containing recombinant porcine epidemic diarrhea virus (PEDV) spike protein induced high levels of neutralizing antibodies in both mice and piglets. However, immunization of piglets with this vaccine resulted in enhancement of disease symptoms and virus replication in vaccine recipients exposed to PEDV challenge. Thus, these observations demonstrate a previously unrecognized challenge of PEDV vaccine research, which has important implications for coronavirus vaccine development.

The Intellectual Property Of Covid-19, Ana Santos Rutschman

All Faculty Scholarship

The response to COVID-19 is indissolubly tied to intellectual property. In an increasingly globalized world in which infectious disease pathogens travel faster and wider than before, the development of vaccines, treatments and other forms of medical technology has become an integral part of public health preparedness and response frameworks. The development of these technologies, and to a certain extent the allocation and distribution of resulting outputs, is informed by intellectual property regimes. These regimes influence the commitment of R&D resources, shape scientific collaborations and, in some cases, may condition the widespread availability of emerging technologies. As seen throughout this chapter, …

Nutritional Aspects Related To Covid-19: A Bibliometric Analysis Using Scopus Database, Arti Muley Dr, Srujana Medithi Dr

Library Philosophy and Practice (e-journal)

Nutrition therapy has lately gained attention as an effective way of combating the novel Coronavirus 2019 (COVID-19), especially to address the immunity in an individual and their overall health. The present study is a bibliometric assessment of research conducted to understand the role of nutrition in treating COVID-19 which was carried out since the pandemic's sudden outburst during 2020 and 2021 and published in the Scopus database. A total of 93 publications were found, and the results were studied by evaluating these documents. The present analysis identifies the active countries where the research was conducted, various types of documents wherein …

December 23, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

All residential and non-residential students, faculty and staff that will be on campus during Winter Term will be required to be tested on campus through Helix Diagnostics with a negative test result. The University will offer free, scheduled testing through Helix Diagnostics prior to the start of Winter Term at scheduled times during the first week of January.

The new Safe Campus 2021 Guidelines for Winter Term are now online on the University’s website. It includes: Testing & Health Services, Safety Measures, Academics & Co-op, Student Life, Facilities and Visiting Campus.

November 20, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

As we approach the Thanksgiving holiday, we want to encourage everyone to be very cautious so as to safely celebrate with loved ones. Stay safe and informed not just for the well-being of your friends and families, but also for our campus community upon your return. This means all of us continuing to practice social distancing, properly wearing a face mask and washing our hands often.

November 16, 2020: Letter From The President- Covid-19 Update, Kettering University

Communication Updates

No abstract provided.

November 15, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

We are currently evaluating the full extent and impact on our campus community of the announcement by the Michigan Governor on Sunday evening. This announcement includes limitations to be imposed statewide effective this Wednesday.

Actions to be taken by the University to be in compliance with local and state directives will be determined and communicated promptly to the campus community.

November 11, 2020: Letter From The President- Covid-19 Town Hall Meeeting, Kettering University

Communication Updates

All students, faculty and staff are invited to join members of the Kettering University’s COVID-19 Response Team for a virtual Town Hall to discuss COVID-19 and the safety measures put in place on campus.

November 3, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

No abstract provided.

November 2, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

No abstract provided.

October 29, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus. In addition to providing updates on a regular basis, the team meets regularly to review, evaluate and address immediate and future issues related to the pandemic. Members of …

October 29, 2020: Letter From The President- Covid-19 Update, Kettering University

Communication Updates

No abstract provided.

October 27, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus. In addition to providing updates on a regular basis, the team meets regularly to review, evaluate and address immediate and future issues related to the pandemic. Members of …

October 25, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus. In addition to providing updates on a regular basis, the team meets regularly to review, evaluate and address immediate and future issues related to the pandemic. Members of …

October 23, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus. In addition to providing updates on a regular basis, the team meets regularly to review, evaluate and address immediate and future issues related to the pandemic. Members of …

October 16, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and to provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus.

October 9, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and to provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus.

October 7, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

The COVID-19 Response Team continues to work with the Genesee County Public Health Department and with the Of ice of the President to adapt to the situation as it evolves and to provide our community with the most current information regarding the COVID-19 pandemic. The University is fully committed to the health and safety of its entire community, and will continue to closely monitor this situation and any others that impact our campus.

October 2, 2020: Covid-19 Campus Update, Kettering University

Communication Updates

It is that time. We are excited and ready to welcome everyone to campus for Fall Term 2020 on October 5 (Monday). But with that comes an important reminder that all students, faculty and staf are expected to demonstrate personal responsibility and compliance to outlined guidelines to keep our campus community safe. Our success is dependent on all of our actions.

This means we wear masks, observe social guidelines and distancing, self-monitor for symptoms, and behave on and of campus in ways that limit the exposure and spread of the coronavirus.

The COVID-19 Response Team and University leadership will continue …

Endothelial Cell Contributions To Covid-19, Alexandra E. Oxford, Fabio Halla, Evan B. Robertson, Brad E. Morrison

Biology Faculty Publications and Presentations

Understanding of the clinical, histological and molecular features of the novel coronavirus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)) has remained elusive. Coronavirus disease 2019 (COVID-19) caused by this virus has unusual clinical presentation with regard to other related coronaviruses. Recent reports suggest that SARS-CoV-2, unlike other related viruses, infects and replicates within endothelial cells, which may explain a significant portion of the observed clinical pathology. Likewise, mounting evidence associates vascular and endothelial cell dysfunction with increased mortality. This review focuses on understanding how endothelial cell pathology is caused by SARS-CoV-2 at the molecular and cellular levels and how …

‘Coronated’ Consumption In The Viral Market, Soonkwan Hong

Markets, Globalization & Development Review

The universal exposure to the virus has disrupted institutions, redefined values, and reshaped systems, including the market. Idling, uncertainty, and liquidity encapsulate the ever-precarious individual lives and the reflexive socio-politico-cultural changes. These conditions and consequences nonetheless create paradoxical opportunities in the viral market. The new meaning of connectivity that promotes high-viscosity relationships and high-visibility identities will transform the market to better acknowledge and support humans and the new sociality.

September 25, 2020: Covid-19 Campus Update 7, Kettering University

Communication Updates

The COVID-19 Response Team and University leadership continue to closely monitor the local, state and national situation in consultation with health experts and in accordance with government guidelines. If conditions change, the University will alter plans to ensure the safety of the campus community. Fall Term 2020 classes begin on October 5. As the University’s COVID-19 Response Team continues to finalize details for the fall, please carefully review these updates.

September 18, 2020: Campus Update 6, Kettering University

Communication Updates

The COVID-19 Response Team and University leadership continue to closely monitor the local, state and national situation in consultation with health experts and in accordance with government guidelines. If conditions change, the University will alter plans to ensure the safety of the campus community. Fall Term 2020 classes begin on October 5. As the University’s COVID-19 Response Team continues to finalize details for the fall, please carefully review these updates.

September 17, 2020: Campus Update, Kettering University

Communication Updates

No abstract provided.

September 11, 2020: Safe Return To Campus Fall 2020, Update 5, Kettering University

Communication Updates

The COVID-19 Response Team and University leadership continue to closely monitor the local, state and national situation in consultation with health experts and in accordance with government guidelines. If conditions change, the University will alter plans to ensure the safety of the campus community. Fall Term 2020 classes begin on October 5. As the University’s COVID-19 Response Team continues to finalize details for the fall, please carefully review these updates.

September 4, 2020: Safe Return To Campus Fall 2020 Update 4, Kettering University

Communication Updates

The COVID-19 Response Team and University leadership continue to closely monitor the local, state and national situation in consultation with health experts and in accordance with government guidelines. If conditions change, the University will alter plans to ensure the safety of the campus community. Fall Term 2020 classes begin on October 5. As the University’s COVID-19 Response Team continues to finalize details for the fall, please carefully review these updates