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Immunology and Infectious Disease Commons

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Full-Text Articles in Immunology and Infectious Disease

Regulation Of Gut Commensal-Specific T Cell Differentiation By Dendritic Cell Subsets, Emilie Russler-Germain May 2021

Regulation Of Gut Commensal-Specific T Cell Differentiation By Dendritic Cell Subsets, Emilie Russler-Germain

Arts & Sciences Electronic Theses and Dissertations

The mammalian gastrointestinal tract can harbor both beneficial commensal organisms important for host health, but also pathogenic organisms capable of intestinal damage. It is therefore important that the host immune system mounts appropriate responses to different intestinal organisms – promoting tolerance to some, controlling the colonization of others, and inducing sterilizing immunity in cases of noxious pathogens. Failure to induce tolerance to commensal organisms may underlie immune-mediated diseases such as human inflammatory bowel disease, while inappropriate tolerance to more harmful organisms has the potential to result in infection, inflammation, or even malabsorption. Adaptive immune responses to intestinal commensal organisms are …


Data From: Recovery From Discrete Wound Severities In Side-Blotched Lizards (Uta Stansburiana): Implications For Energy Budget, Locomotor Performance, And Oxidative Stress, Susannah S. French, Spencer B. Hudson Feb 2021

Data From: Recovery From Discrete Wound Severities In Side-Blotched Lizards (Uta Stansburiana): Implications For Energy Budget, Locomotor Performance, And Oxidative Stress, Susannah S. French, Spencer B. Hudson

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Wounding events (predation attempts, competitive combat) result in injuries and/or infections that induce integrated immune responses for the recovery process. Despite the survival benefits of immunity in this context, the costs incurred may require investment to be diverted from traits contributing to immediate and/or future survival, such as locomotor performance and oxidative status. Yet, whether trait constraints manifest likely depends on wound severity and the implications for energy budget. For this study, food intake, body mass, sprint speed, and oxidative indices (reactive oxygen metabolites, antioxidant capacity) were monitored in male side-blotched lizards (Uta stansburiana) healing from cutaneous wounds of discrete …


Data For "Arch_Covid_Crowding_Vc", Wayne Freimund, Zachary D. Miller Jan 2021

Data For "Arch_Covid_Crowding_Vc", Wayne Freimund, Zachary D. Miller

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Monitoring of visitor use in Arches National Park to assess social distancing behaviors of visitors during the COVID-19 pandemic.