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Immunology and Infectious Disease Commons™
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Full-Text Articles in Immunology and Infectious Disease
Measuring Immune Responsiveness In Xenopus Laevis Using Phytohaemagglutanin (Pha), Kevin Kinney, Skyler Majors, Madelyn Lee, Scott Espich, Erika Kischuk
Measuring Immune Responsiveness In Xenopus Laevis Using Phytohaemagglutanin (Pha), Kevin Kinney, Skyler Majors, Madelyn Lee, Scott Espich, Erika Kischuk
Annual Student Research Poster Session
Phytohaemagglutanin (PHA) is a red kidney bean extract that has been used to stimulate an immunological T cell response in a variety of animals. This procedure has become very popular method to analyze an individual animal’s ability to trigger an immunological response.(Brown 2014) PHA skin testing has been used in a variety of avian, mice, lizard, and amphibian species where it is injected into the muscle, skin, or webbing of an animal and then recording the amount of swelling before and after the injection.(Smits 1999) We are using the amphibian Xenopus laevis to test 1) their immune reaction under normal …