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Immunology and Infectious Disease Commons

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Biochemistry, Biophysics, and Structural Biology

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Full-Text Articles in Immunology and Infectious Disease

The Specific Immune Response In Rainbow Trout: Somatic Hypermutation And Vh Gene Utilization, Teresa D. Lewis Jan 2000

The Specific Immune Response In Rainbow Trout: Somatic Hypermutation And Vh Gene Utilization, Teresa D. Lewis

Dissertations, Theses, and Masters Projects

The study of antibody responses in prominent aquaculture species such as the rainbow trout, Oncorhynchus mykiss, can facilitate vaccine development and contribute to producing useful paradigms of adaptive immunity in lower vertebrates. Thus, it is essential to identify genes responsible for antibody responses. In the mouse model, hybridoma technology allows for the association of monoclonal antibodies possessing various affinities for antigen with specific VH sequences, gene family utilization, and other molecular events (i.e. somatic hypermutation) that occur during the specific immune response. The absence of a comparable hybridoma technology in piscine systems has limited similar studies of fish immunogenetics to …


Immunological Identification Of A Centrin Homologue In The Red Alga Gracilaria Tikvahiae, Christopher Lee Dassler Jan 1991

Immunological Identification Of A Centrin Homologue In The Red Alga Gracilaria Tikvahiae, Christopher Lee Dassler

Dissertations, Theses, and Masters Projects

No abstract provided.