Genetics and Genomics Commons^™

Kinetics Of The Chromosome 14 Microrna Cluster Ortholog And Its Potential Role During Placental Development In The Pregnant Mare, Pouya Dini, Peter Daels, Shavahn C. Loux, Alejandro Esteller-Vico, Mariano Carossino, Kirsten E. Scoggin, Barry A. Ball

Maxwell H. Gluck Equine Research Center Faculty Publications

Background: The human chromosome 14 microRNA cluster (C14MC) is a conserved microRNA (miRNA) cluster across eutherian mammals, reported to play an important role in placental development. However, the expression kinetics and function of this cluster in the mammalian placenta are poorly understood. Here, we evaluated the expression kinetics of the equine C24MC, ortholog to the human C14MC, in the chorioallantoic membrane during the course of gestation.

Results: We demonstrated that C24MC-associated miRNAs presented a higher expression level during early stages of pregnancy, followed by a decline later in gestation. Evaluation of one member of C24MC (miR-409-3p) by in situ hybridization …

Genomic Investigation Of Beta Agonist Supplementation And Heat Stress In Livestock Species, Rachel Marie Kubik

College of Education and Human Sciences: Dissertations, Theses, and Student Research

β-adrenergic agonists (β-AA), commonly fed to cattle during the last 20-40 days of the finishing period, improve muscle growth by decreasing adipose deposition and increasing muscle accretion. In most cases, final live weights, hot carcass weight and average daily gain have all been shown to increase when β-AA are feed while fed intake, back fat, and marbling all decrease. Two β-AA, Ractopamine HCl (β1-AA) and Zilpaterol HCl (β2-AA) are currently approved for use in beef cattle in the United States. Converse to the beneficial effects of β-AA, heat stress in livestock decreases production efficiency and growth. There have also been …