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Full-Text Articles in Genetics and Genomics
Characterization And Amplification Of Retrotransposable Elements Platy-1 And Alu In The Cebidae Lineage Of Platyrrhine Primates, Jessica Storer
Characterization And Amplification Of Retrotransposable Elements Platy-1 And Alu In The Cebidae Lineage Of Platyrrhine Primates, Jessica Storer
LSU Doctoral Dissertations
Alu mobile elements are much more than “junk DNA”. Inherent properties such as high copy number, small ~300 bp size, and their nearly homoplasy-free nature make these elements particularly useful in resolving primate phylogenies. In addition, shared sequence features and identity with the Alu element allow for discovery of new SINE retrotransposons, such as the Platyrrhine-limited Platy-1 element. Building on previous research of subfamily analysis, the Platy-1 and Alu elements can be used not only to explore the controversial New World monkey (NWM) phylogeny, but also the mode and tempo of their amplification in different primate genera and species.
Chapter …
Computational Analysis Of Papionini Evolution Using Alu Insertions, Vallmer Edward Jordan Ii
Computational Analysis Of Papionini Evolution Using Alu Insertions, Vallmer Edward Jordan Ii
LSU Doctoral Dissertations
Alu elements are primate specific retrotransposons that have remained active throughout the course of primate evolution. As a result of this sustained mobilization. Alu elements are present in greater copy number in primate genomes than any other transposable element. An average of over one million Alu elements has been identified in every sequenced haplorrhine genome to date. These characteristics qualify Alu elements as ideal characters for studying evolutionary relationship among primates.
The increasing availability of whole genome sequencing data presents novel challenges and opportunities for comparative genomic analyses. Genomic data is now publicly available for most primate species. Such an …
An Analysis Of Alu Elements In Baboons, Cody James Steely
An Analysis Of Alu Elements In Baboons, Cody James Steely
LSU Doctoral Dissertations
Transposable elements compose a large portion of mammalian genomes and are estimated to make up anywhere from ~45% - ~70% of the human genome. Alu elements are primate-specific retrotransposons that are found in high copy number (> 1 million copies) and are spread throughout the genome. These elements are the most commonly repeated sequence in the human genome and have contributed to a number of disease states in humans. Alu elements are useful markers for population genetics and phylogenetics and have proven valuable in understanding difficult to determine relationships between species and within populations.
Baboons (genus Papio) are spread throughout …