Genetics and Genomics Commons^™

Playing God, Jeff Ploegstra

Faculty Work Comprehensive List

"Technically speaking, animals and plants that we have selectively bred are genetically modified organisms (GMOs)."

Posting about the benefits and dangers of genetic modification from In All Things - an online hub committed to the claim that the life, death, and resurrection of Jesus Christ has implications for the entire world.

http://inallthings.org/playing-god/

Novel Approach To Identify Optimal Metabotypes Of Elongase And Desaturase Activities In Prevention Of Acute Coronary Syndrome, Nathan L. Tintle, John W. Newman, Gregory C. Shearer

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Both metabolomic and genomic approaches are valuable for risk analysis, however typical approaches evaluating differences in means do not model the changes well. Gene polymorphisms that alter function would appear as distinct populations, or metabotypes, from the predominant one, in which case risk is revealed as changed mixing proportions between control and case samples. Here we validate a model accounting for mixed populations using biomarkers of fatty acid metabolism derived from a case/control study of acute coronary syndrome subjects in which both metabolomic and genomic approaches have been used previously. We first used simulated data to show improved power and …