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Molecular Genetic Investigation Of Twins, Families, And Populations, Jeffrey John Beck
Molecular Genetic Investigation Of Twins, Families, And Populations, Jeffrey John Beck
Dissertations and Theses
Twins have long been of interest for illuminating genetic and environmental influences on human traits and diseases. These explorations have been accelerated by the substantial amount of information collected from twins and their families participating in twin registers around the world. In this dissertation, I review what is known and what remains unknown about the biology and genetics of twins and the underlying twinning process. To elucidate additional genetic factors of the twinning process, I employed pedigree-based analysis to identify genetic regions shared among distantly related mothers of dizygotic twins. The shared regions may potentially contain rare genetic variants with …