Open Access. Powered by Scholars. Published by Universities.®

Genetics and Genomics Commons

Open Access. Powered by Scholars. Published by Universities.®

Department of Animal Science: Faculty Publications

Series

2020

GWAS

Articles 1 - 2 of 2

Full-Text Articles in Genetics and Genomics

Genomic Analysis Of Igg Antibody Response To Common Pathogens In Commercial Sows In Health-Challenged Herds, Leticia P. Sanglard, Piggen Canada, Benny E. Mote, Philip Willson, John C.S. Harding, Graham S. Plastow, Jack C.M. Dekkers, Nick V.L. Serão Oct 2020

Genomic Analysis Of Igg Antibody Response To Common Pathogens In Commercial Sows In Health-Challenged Herds, Leticia P. Sanglard, Piggen Canada, Benny E. Mote, Philip Willson, John C.S. Harding, Graham S. Plastow, Jack C.M. Dekkers, Nick V.L. Serão

Department of Animal Science: Faculty Publications

Losses due to infectious diseases are one of the main factors affecting productivity in the swine industry, motivating the investigation of disease resilience-related traits for genetic selection. However, these traits are not expected to be expressed in the nucleus herds, where selection is performed. One alternative is to use information from the commercial level to identify and select nucleus animals genetically superior for coping with pathogen challenges. In this study, we analyzed the genetic basis of antibody (Ab) response to common infectious pathogens in health-challenged commercial swine herds as potential indicator traits for disease resilience, including Ab response to influenza …


Genome-Wide Association Study To Identify Genetic Loci Associated With Gastrointestinal Nematode Resistance In Katahdin Sheep, G. M. Becker, K. M. Davenport, Joan M. Burke, Ronald M. Lewis, J. E. Miller, J. L.M. Morgan, D. R. Notter, B. M. Murdoch Jan 2020

Genome-Wide Association Study To Identify Genetic Loci Associated With Gastrointestinal Nematode Resistance In Katahdin Sheep, G. M. Becker, K. M. Davenport, Joan M. Burke, Ronald M. Lewis, J. E. Miller, J. L.M. Morgan, D. R. Notter, B. M. Murdoch

Department of Animal Science: Faculty Publications

Resistance to gastrointestinal nematodes has previously been shown to be a moderately heritable trait in some breeds of sheep, but the mechanisms of resistance are not well understood. Selection for resistance currently relies upon faecal egg counts (FEC), blood packed cell volumes and FAMACHA visual indicator scores of anaemia. Identifying genomic markers associated with disease resistance would potentially improve the selection process and provide a more reliable means of classifying and understanding the biology behind resistant and susceptible sheep. A GWAS was conducted to identify possible genetic loci associated with resistance to Haemonchus contortus in Katahdin sheep. Forty animals were …