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Full-Text Articles in Genetics and Genomics
Application Of Subspace Clustering In Dna Sequence Analysis, Tim Wallace, Ali Sekmen, Xiaofei Wang
Application Of Subspace Clustering In Dna Sequence Analysis, Tim Wallace, Ali Sekmen, Xiaofei Wang
Computer Science Faculty Research
Identification and clustering of orthologous genes plays an important role in developing evolutionary models such as validating convergent and divergent phylogeny and predicting functional proteins in newly sequenced species of unverified nucleotide protein mappings. Here, we introduce an application of subspace clustering as applied to orthologous gene sequences and discuss the initial results. The working hypothesis is based upon the concept that genetic changes between nucleotide sequences coding for proteins among selected species and groups may lie within a union of subspaces for clusters of the orthologous groups. Estimates for the subspace dimensions were computed for a small population sample. …