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Full-Text Articles in Genetics and Genomics
Developing A Novel Place Preference Assay To Compare Drosophila Species Over Time, Martha M. Brinson
Developing A Novel Place Preference Assay To Compare Drosophila Species Over Time, Martha M. Brinson
Honors Theses
Across phylogeny, integration of external factors, memory, and internal states of the organism dictate organismal behavior and mechanisms. The underlying genetic components can affect these behaviors such as in genomic changes arising from speciation. In this thesis, a new place preference assay was evaluated in the analysis and investigation of two species of Drosophila flies (D. melanogaster and D. simulans) to measure similarities and differences and their attraction to two different food substrates. Sleep and circadian measurements were also recorded during experimentation. The Drosophila Activity Monitor 5M (DAM5M) System and Sleep Circadian Analysis MATLAB Program (SCAMP) analysis were …
Characterization Of Cis-Regulatory Elements Controlling Repo Transcription In Drosophila Melanogaster, Robert Johnson
Characterization Of Cis-Regulatory Elements Controlling Repo Transcription In Drosophila Melanogaster, Robert Johnson
Electronic Theses and Dissertations
The glial cells missing (gcm) gene has been identified as a "master regulator" of glial cell fate in the fruit fly Drosophila . However, the gcm gene is also expressed in and required for the development of larval macrophages and tendon cells, and lamina neurons in the adult CNS. Thus, the Gcm protein activates the transcription of different sets of genes in different developmental contexts. How the Gcm protein regulates these different outcomes is not known. My long-term goal is to identify proteins that collaborate with Gcm to promote the transcriptional activation of Gcm target genes specifically in glial cells, …