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Full-Text Articles in Genetics and Genomics
Genomics Of Mature And Immature Olfactory Sensory Neuron, Timothy S. Mcclintock
Genomics Of Mature And Immature Olfactory Sensory Neuron, Timothy S. Mcclintock
Physiology Research Data
The Excel file contains probabilistic predictions of which genes are expressed in mature versus immature olfactory sensory neurons, versus the sum of all other cell types in the olfactory epithelium. Responses to bulbectomy, which differentially affects mature and immature olfactory sensory neurons, supports these predictions.
A Comparative Genomics Approach To Using High-Throughput Gene Expression Data To Study Limb Regeneration In Ambystoma Mexicanum And Danio Rerio: Developing A More Completely Annotated Database, Justin Bolinger
Honors College
Axolotl (Ambystoma mexicanum) and the zebrafish (Danio rerio) represent organisms extensively studied because of their remarkable capability of fully regenerating completely functional tissues after a traumatic event takes place. However, the research conducted with regards to the genomics of these two organisms has remained fairly independent of each other. The intent of this study is to bridge this gap and connect genes between axolotl and the zebrafish by use a “Rosetta stone” framework to develop a database comparing gene expression data obtained from both microarraybased experiments and high-throughput DNA sequencing of axolotl and zebrafish mRNA and miRNA. Using gene data …
Genomics Of Mature And Immature Olfactory Sensory Neurons, Melissa D. Nickell, Patrick Breheny, Arnold J. Stromberg, Timothy S. Mcclintock
Genomics Of Mature And Immature Olfactory Sensory Neurons, Melissa D. Nickell, Patrick Breheny, Arnold J. Stromberg, Timothy S. Mcclintock
Physiology Faculty Publications
The continuous replacement of neurons in the olfactory epithelium provides an advantageous model for investigating neuronal differentiation and maturation. By calculating the relative enrichment of every mRNA detected in samples of mature mouse olfactory sensory neurons (OSNs), immature OSNs, and the residual population of neighboring cell types, and then comparing these ratios against the known expression patterns of >300 genes, enrichment criteria that accurately predicted the OSN expression patterns of nearly all genes were determined. We identified 847 immature OSN-specific and 691 mature OSN-specific genes. The control of gene expression by chromatin modification and transcription factors, and neurite growth, protein …
Shelling Out For Genomics, Timothy S. Mcclintock, Charles D. Derby
Shelling Out For Genomics, Timothy S. Mcclintock, Charles D. Derby
Physiology Faculty Publications
A report on the symposium 'Genomic and Proteomic Approaches to Crustacean Biology' held as part of the Society for Integrative and Comparative Biology 2006 Annual Meeting, Orlando, USA, 4-8 January 2006.