Open Access. Powered by Scholars. Published by Universities.®
- Keyword
Articles 1 - 23 of 23
Full-Text Articles in Genetics and Genomics
Gmr36a08, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr36a08, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 49927
- ID - GMR36A08
- Location - 2R: 18120673, 18124576
- Base pairs - 3903
Gmr40e08, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr40e08, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 41238
- ID - GMR40E08
- Location - 2R: 18162090, 18165058
- Base pairs - 2968
Gmr42a07, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr42a07, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 45284
- ID - GMR42A07
- Location - 2R: 18146520, 18150306
- Base pairs - 3786
Gmr36a10, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr36a10, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 49373
- ID - GMR36A10
- Location - 2R: 18116788, 18120701
- Base pairs - 3913
Gmr40c09, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr40c09, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer
- ID - GMR40C09
- Location - 2R: 18132203, 18134987
- Base pairs - 2784
Gmr41f05, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr41f05, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 50133
- ID - GMR41F05
- Location - 2R: 18139042, 18142672
- Base pairs - 3630
Gmr35a04, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr35a04, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer
- ID - GMR35A04
- Location - 2R: 18125755, 18128365
- Base pairs - 2610
Gmr39h01, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr39h01, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 50066
- ID - GMR39H01
- Location - 2R: 18153797, 18156108
- Base pairs - 2311
Gmr42e10, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr42e10, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer
- ID - GMR42E10
- Location - 2R: 18133506, 18137474
- Base pairs - 3968
Gmr41c04, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr41c04, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer
- ID - GMR41C04
- Location -2R: 18143594, 18147064
- Base pairs - 3470
Gmr40c05, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr40c05, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 45682
- ID - GMR40C05
- Location - 2R: 18141630, 18144381
- Base pairs - 2751
Gmr41h07, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr41h07, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 46241
- ID - GMR41H07
- Location - 2R: 18150920, 18154671
- Base pairs - 3751
Gmr42h01, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
Gmr42h01, Anuradha Venkatakrishnan Chimata, Oorvashi Roy Puli, Amit Singh
DVE Enhancer Sequences Utilized in GMR Line
dve enhancer 48150
- ID - GMR42H01
- Location - 2R: 18158419, 18162751
- Base pairs - 4332
45442 (Gmr18d08), Neha Gogia, Ankita Sarkar, Amit Singh
45442 (Gmr18d08), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 45442
- Id - GMR 18D08
- Location - 2L:2446783,2449086
- Base pairs – 2303 bp
45437 (Gmr18b08), Neha Gogia, Ankita Sarkar, Amit Singh
45437 (Gmr18b08), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 45437
- Id - GMR18B08
- Location - 2L:2455899,2457734
- Base pairs – 1835 bp
47472 (Gmr16g02), Neha Gogia, Ankita Sarkar, Amit Singh
47472 (Gmr16g02), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 47472
- Id - GMR16G02
- Location 2L:2425041, 2428154
- Base pairs – 3113 bp
48770 (Gmr17e04), Neha Gogia, Ankita Sarkar, Amit Singh
48770 (Gmr17e04), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 48770
- Id - GMR17E04
- Location 2L: 2428913..2432834
- Base pairs – 3921 bp
48784 (Gmr17g08), Neha Gogia, Ankita Sarkar, Amit Singh
48784 (Gmr17g08), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 48784
- Id - GMR 17G08
- Location 2L:2450278,2451074
- Base pairs – 796 bp
49283 (Gmr19c03), Neha Gogia, Ankita Sarkar, Amit Singh
49283 (Gmr19c03), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 49283
- Id - GMR19C03
- Location - 2L:2440970,2444735
- Base pairs – 3765 bp
48839 (Gmr19b04), Neha Gogia, Ankita Sarkar, Amit Singh
48839 (Gmr19b04), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 48839
- Id - GMR19B04,
- Location - 2L:2432214,2435785
- Base pairs – 3571 bp
45833 (Gmr19d09), Neha Gogia, Ankita Sarkar, Amit Singh
45833 (Gmr19d09), Neha Gogia, Ankita Sarkar, Amit Singh
Dpp Enhancer Sequences Utilized in GMR Line
dpp enhancer - 45833
- Id - GMR19D09
- Location - 2L:2435128,2438996
- Base pairs – 3868 bp
Homeotic Gene Teashirt (Tsh) Has A Neuroprotective Function In Amyloid-Beta 42 Mediated Neurodegeneration, Michael T. Moran, Meghana Tare, Madhuri Kango-Singh, Amit Singh
Homeotic Gene Teashirt (Tsh) Has A Neuroprotective Function In Amyloid-Beta 42 Mediated Neurodegeneration, Michael T. Moran, Meghana Tare, Madhuri Kango-Singh, Amit Singh
Biology Faculty Publications
Background: Alzheimer's disease (AD) is a debilitating age related progressive neurodegenerative disorder characterized by the loss of cognition, and eventual death of the affected individual. One of the major causes of AD is the accumulation of Amyloid-beta 42 (Aβ42) polypeptides formed by the improper cleavage of amyloid precursor protein (APP) in the brain. These plaques disrupt normal cellular processes through oxidative stress and aberrant signaling resulting in the loss of synaptic activity and death of the neurons. However, the detailed genetic mechanism(s) responsible for this neurodegeneration still remain elusive.
Methodology/Principal Findings: We have generated a transgenic Drosophila eye model where …
Dorsal Eye Selector Pannier (Pnr) Suppresses The Eye Fate To Define Dorsal Margin Of The Drosophila Eye, Sarah M. Oros, Meghana Tare, Madhuri Kango-Singh, Amit Singh
Dorsal Eye Selector Pannier (Pnr) Suppresses The Eye Fate To Define Dorsal Margin Of The Drosophila Eye, Sarah M. Oros, Meghana Tare, Madhuri Kango-Singh, Amit Singh
Biology Faculty Publications
Axial patterning is crucial for organogenesis. During Drosophila eye development, dorso-ventral (DV) axis determination is the first lineage restriction event. The eye primordium begins with a default ventral fate, on which the dorsal eye fate is established by expression of the GATA-1 transcription factor pannier (pnr). Earlier, it was suggested that loss of pnr function induces enlargement in the dorsal eye due to ectopic equator formation. Interestingly, we found that in addition to regulating DV patterning, pnr suppresses the eye fate by downregulating the core retinal determination genes eyes absent (eya), sine oculis (so) and dacshund (dac) to define the …